2,2,2-Trichloro-1-(6-methoxy-1H-indol-3-yl)ethan-1-one CAS 1016163-40-8

Purity 97%+In StockPharmaceutical Standards
CAS No.1016163-40-8
Molecular FormulaC11H8Cl3NO2
Molecular Weight292.55 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2,2,2-Trichloro-1-(6-methoxy-1H-indol-3-yl)ethan-1-one CAS 1016163-40-8 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2,2,2-Trichloro-1-(6-methoxy-1H-indol-3-yl)ethan-1-one.

CATO supplies 2,2,2-Trichloro-1-(6-methoxy-1H-indol-3-yl)ethan-1-one (CAS 1016163-40-8), a certified reference material (molecular formula C11H8Cl3NO2, MW 292.55 g/mol) for analytical method development and quality control.

Based on its molecular formula C11H8Cl3NO2, 2,2,2-Trichloro-1-(6-methoxy-1H-indol-3-yl)ethan-1-one contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 292.55 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC11H8Cl3NO2
Molecular Weight292.55 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1988
Halogen ContentCl-containing
Nitrogen Atoms1

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