1,2-Difluoro-3-nitro-5-(trifluoromethyl)benzene CAS 101646-01-9
| CAS No. | 101646-01-9 |
| Molecular Formula | C7H2F5NO2 |
| Molecular Weight | 227.09 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1,2-Difluoro-3-nitro-5-(trifluoromethyl)benzene.
CATO supplies 1,2-Difluoro-3-nitro-5-(trifluoromethyl)benzene (CAS 101646-01-9), a certified reference material (molecular formula C7H2F5NO2, MW 227.09 g/mol) for analytical method development and quality control.
Structurally, 1,2-Difluoro-3-nitro-5-(trifluoromethyl)benzene (C7H2F5NO2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 227.09 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 1,2-Difluoro-3-nitro-5-(trifluoromethyl)benzene meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H2F5NO2 |
| Molecular Weight | 227.09 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Difluoro Standards
- 1,2-Difluoro-4-nitro-5-(trifluoromethyl)benzene (CAS 117392-82-2)
- 1,3-Difluoro-2-nitro-5-(trifluoromethyl)benzene (CAS 1226805-43-1)
- 1,3-Difluoro-4-nitro-2-(trifluoromethyl)benzene (CAS 123973-36-4)
- 2,4-Difluoro-6-nitrobenzotrifluoride (CAS 1803730-36-0)
- 2,6-Difluoro-4-nitrobenzotrifluoride (CAS 1803787-00-9)
- 3,5-Difluoro-2-nitrobenzotrifluoride (CAS 1806370-63-7)
- 1,5-Difluoro-2-nitro-4-(trifluoromethyl)benzene (CAS 35010-29-8)
- 2,5-Difluoro-1-nitro-3-(trifluoromethyl)benzene (CAS 2837-22-1)
Recommended Standards
- 1-Bromo-4-(1,1-difluoroethyl)benzene (CAS 1000994-95-5)
- 5-Chloromethyl-2-(4-chlorophenyl)-1H-imidazole (CAS 1053657-20-7)
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