1-(3,4-Difluorobenzoyl)-1,4-diazepane CAS 1016683-49-0
| CAS No. | 1016683-49-0 |
| Molecular Formula | C12H14F2N2O |
| Molecular Weight | 240.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 240.25 g/mol gives 1-(3,4-Difluorobenzoyl)-1,4-diazepane distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
1-(3,4-Difluorobenzoyl)-1,4-diazepane (CAS 1016683-49-0) is a high-purity analytical reference standard with the molecular formula C12H14F2N2O and a molecular weight of 240.25 g/mol.
The molecular framework of 1-(3,4-Difluorobenzoyl)-1,4-diazepane (C12H14F2N2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 1-(3,4-Difluorobenzoyl)-1,4-diazepane meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H14F2N2O |
| Molecular Weight | 240.25 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Difluorobenzoyl Standards
- 1-(3,5-Difluorobenzoyl)-1,4-diazepane (CAS 1016704-74-7)
- 1-(2,5-Difluorobenzoyl)-1,4-diazepane (CAS 1016800-39-7)
- 1-(2,4-Difluorobenzoyl)-3-methylpiperazine (CAS 1240564-71-9)
- 1-(2,5-Difluorobenzoyl)-3-methylpiperazine (CAS 1240564-77-5)
- 1-(3,4-Difluorobenzoyl)-3-methylpiperazine (CAS 1240564-95-7)
- 1-(2,5-Difluorobenzoyl)-2-methylpiperazine (CAS 1240565-38-1)
- 1-(3,5-Difluorobenzoyl)-2-methylpiperazine (CAS 1240566-03-3)
- 1-(3,4-Difluorobenzoyl)-2-methylpiperazine (CAS 1240570-47-1)
Recommended Standards
- 2,6-Difluoro-N-(piperidin-4-yl)benzamide (CAS 1016497-11-2)
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- 2,4,7,10,13-Pentaoxatetradecane-1,14-diol (CAS 100208-40-0)
- 1-(3,4,5-Trimethoxybenzoyl)-1,4-diazepane (CAS 99822-56-7)
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