{2-[4-(4-fluorophenyl)piperazin-1-yl]pyridin-4-yl}methanamine CAS 1016712-41-6

Purity 97%+In StockPharmaceutical Standards
CAS No.1016712-41-6
Molecular FormulaC16H19FN4
Molecular Weight286.35 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

{2-[4-(4-fluorophenyl)piperazin-1-yl]pyridin-4-yl}methanamine CAS 1016712-41-6 chemical structure

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

{2-[4-(4-fluorophenyl)piperazin-1-yl]pyridin-4-yl}methanamine (CAS 1016712-41-6) is a high-purity analytical reference standard with the molecular formula C16H19FN4 and a molecular weight of 286.35 g/mol.

The molecular framework of {2-[4-(4-fluorophenyl)piperazin-1-yl]pyridin-4-yl}methanamine (C16H19FN4) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC16H19FN4
Molecular Weight286.35 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1988
Halogen ContentF-containing
Nitrogen Atoms4

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