N’-hydroxy-2-phenoxypyridine-3-carboximidamide CAS 1016752-79-6
| CAS No. | 1016752-79-6 |
| Molecular Formula | C12H11N3O2 |
| Molecular Weight | 229.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of N’-hydroxy-2-phenoxypyridine-3-carboximidamide (C12H11N3O2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
N’-hydroxy-2-phenoxypyridine-3-carboximidamide (CAS 1016752-79-6) is a high-purity analytical reference standard with the molecular formula C12H11N3O2 and a molecular weight of 229.23 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), N’-hydroxy-2-phenoxypyridine-3-carboximidamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H11N3O2 |
| Molecular Weight | 229.23 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Nitrogen Atoms | 3 |
Related N Standards
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Recommended Standards
- 5-cyclopropyl-2-phenyl-1,3-oxazole-4-carboxylic acid (CAS 1016761-70-8)
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- 2-((3-Fluoro-4-methoxyphenyl)sulfonyl)acetonitrile (CAS 1015603-63-0)
- 3-Ethyl-2-(4-methylthiazol-2-yl)-4H-pyrido[1,2-a]pyrimidin-4-one (CAS 918891-49-3)
- 4-amino-2-(piperidin-1-yl)benzamide (CAS 1311316-53-6)
- 1-(1-(3,4-Dimethylcyclohexyl)-1H-pyrazol-4-yl)-2,2,2-trifluoroethan-1-one (CAS 1561292-93-0)
- Monodecyl Phthalate (CAS 24539-60-4)
- 5-Bromo-N,4-dimethyl-N-((tetrahydro-2H-pyran-4-yl)methyl)pyridin-2-amine (CAS 1220036-21-4)
- 2-[2-(dimethylamino)ethoxy]pyridin-4-amine (CAS 908117-05-5)
- 2-((3-Cyanobenzyl)thio)acetic acid (CAS 887090-48-4)
- Butane-1,4-disulfonyl dichloride (CAS 3079-82-1)
- 2-(3-Bromobenzyl)thiazol-4-amine (CAS 885279-46-9)
- Peptide Impurity 06 (CAS CATO-CPTD788806)
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