4-Ethoxy-3-fluorobenzene-1-sulfonyl chloride CAS 1016756-58-3
| CAS No. | 1016756-58-3 |
| Molecular Formula | C8H8ClFO3S |
| Molecular Weight | 238.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 4-Ethoxy-3-fluorobenzene-1-sulfonyl chloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies 4-Ethoxy-3-fluorobenzene-1-sulfonyl chloride (CAS 1016756-58-3), a certified reference material (molecular formula C8H8ClFO3S, MW 238.66 g/mol) for analytical method development and quality control.
The molecular framework of 4-Ethoxy-3-fluorobenzene-1-sulfonyl chloride (C8H8ClFO3S) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C8H8ClFO3S |
| Molecular Weight | 238.66 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F/Cl-containing |
| Sulfur Atoms | 1 |
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Recommended Standards
- Methyl 5-(chlorosulfonyl)-2-methyl-3-furoate (CAS 306936-35-6)
- 2-(4-Fluorophenoxy)ethanesulfonyl chloride (CAS 1018548-27-0)
- methyl 4-(chlorosulfonyl)-5-methyl-2-furoate (CAS 344308-91-4)
- 1-Chloro-2-(difluoro(phenyl)methyl)benzene (CAS 1068570-00-2)
- N-(furan-2-ylmethyl)-2-(2-nitrophenoxy)ethan-1-amine hydrochloride (CAS 1609407-41-1)
- (2-Bromo-6-chlorophenyl)methanamine (CAS 1261471-96-8)
- (R)-Piperidine-2-carbonitrile (CAS 1434126-85-8)
- 2-Bromo-3,6-dimethoxybenzyl alcohol, 97% (CAS 327164-05-6)
- 2-Butoxyethan-1-amine (CAS 6338-52-9)
- 2-({[(tert-butoxy)carbonyl]amino}methyl)-4,4-dimethylpentanoic acid (CAS 1694853-66-1)
- 1-(5-Bromo-2-fluorophenyl)pentan-1-one (CAS 1280786-93-7)
- Nafcillin Sulfoxide (CAS 41061-20-5)
- Triethoxy(p-tolyl)silane (CAS 18412-57-2)
- Tirzepatide Impurity 35 (CAS CATO-C4X-324035)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com