3-{[4-(Trifluoromethoxy)benzyl]thio}propanoic acid CAS 1016775-83-9
| CAS No. | 1016775-83-9 |
| Molecular Formula | C11H11F3O3S |
| Molecular Weight | 280.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system, 3-{[4-(Trifluoromethoxy)benzyl]thio}propanoic acid is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 280.26 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies 3-{[4-(Trifluoromethoxy)benzyl]thio}propanoic acid (CAS 1016775-83-9), a certified reference material (molecular formula C11H11F3O3S, MW 280.26 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H11F3O3S |
| Molecular Weight | 280.26 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F-containing |
| Sulfur Atoms | 1 |
Related Trifluoromethoxy Standards
- 3-({[3-(trifluoromethoxy)phenyl]methyl}sulfanyl)propanoic acid (CAS 1189749-86-7)
- 1-(2-(Trifluoromethoxy)-[1,1'-biphenyl]-3-yl)ethanone (CAS 675596-36-8)
- 2-[4-(Trifluoromethoxy)phenoxy]isonicotinonitrile (CAS 1417568-82-1)
- 2-(4-(Trifluoromethoxy)phenoxy)nicotinonitrile (CAS 1508040-43-4)
- {4-[4-(Trifluoromethoxy)phenyl]phenyl}boronic acid (CAS 501944-50-9)
- 4-Trifluoromethoxy-2-biphenyl)boronic acid (CAS 2121514-20-1)
- 3'-(Trifluoromethoxy)biphenyl-3-carboxylic acid (CAS 1215206-30-6)
- 4-(4-(Trifluoromethoxy)phenoxy)benzaldehyde (CAS 137736-08-4)
Recommended Standards
- 5,6,7,8-Tetrahydronaphthalen-1-yl trifluoromethanesulfonate (CAS 101533-70-4)
- 2-[2-(6-oxo-1,6-dihydropyridazine-3-amido)-1,3-thiazol-4-yl]acetic acid (CAS 1098367-82-8)
- 2526AE 400073-81-6 C14H11F3N2O N-(2-Aminophenyl)-4-(trifluoromethyl)benzamide (CAS 400073-81-6)
- N'-phenyl-3-(trifluoromethyl)benzohydrazide (CAS 36457-10-0)
- bis(1-ethyl-1-methylguanidine), sulfuric acid (CAS 1798040-90-0)
- Ethyl 2-(pyrazin-2-yl)pyrimidine-5-carboxylate (CAS 1447606-82-7)
- 3-(Cyclohexylmethyl)pyrrolidine (CAS 1220038-54-9)
- Methyl 1-(4-bromophenyl)-5-oxo-2,5-dihydro-1H-1,2,4-triazole-3-carboxylate (CAS 1000573-63-6)
- Crisaborole Impurity 147 (CAS CATO-C4X-202147)
- Benzyl 2-(2-(cyclopropylamino)pyridin-3-yl)piperidine-1-carboxylate (CAS 1352510-61-2)
- 3-aminooxolane-3-carboxamide (CAS 1342406-32-9)
- (3-Carbamothioylphenyl)boronic acid (CAS 850568-10-4)
- (4-(2-(4-Ethylpiperazin-1-yl)ethoxy)-3-fluorophenyl)boronic acid (CAS 1704064-13-0)
- Tirzepatide Impurity 20 (CAS CATO-C4X-324020)
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