2-chloro-6-fluoro-quinoline-3-carboxylic acid CAS 1017222-23-9

Purity 97%+In StockPharmaceutical Standards
CAS No.1017222-23-9
Molecular FormulaC10H15ClFNO2
Molecular Weight235.68 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-chloro-6-fluoro-quinoline-3-carboxylic acid CAS 1017222-23-9 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-chloro-6-fluoro-quinoline-3-carboxylic acid.

2-chloro-6-fluoro-quinoline-3-carboxylic acid (CAS 1017222-23-9), molecular formula C10H15ClFNO2 and molecular weight 235.68 g/mol, is a CATO reference standard with documented purity and traceability.

Structurally, 2-chloro-6-fluoro-quinoline-3-carboxylic acid (C10H15ClFNO2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 3.0, corresponding to approximately 3 ring(s) or double-bond equivalent(s). With a molecular weight of 235.68 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 2-chloro-6-fluoro-quinoline-3-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC10H15ClFNO2
Molecular Weight235.68 g/mol
AppearanceWhite to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)3.0
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1988
Halogen ContentF/Cl-containing
Nitrogen Atoms1

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