Dimefline Impurity 8 CAS 101723-78-8
| CAS No. | 101723-78-8 |
| Molecular Formula | C18H16O4 |
| Molecular Weight | 296.32 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Dimefline Impurity 8 (CAS 101723-78-8), a pharmacopoeial impurity reference standard (molecular formula C18H16O4, MW 296.32 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Dimefline Impurity 8 (C18H16O4) contains a flavonoid core, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 296.32 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H16O4 |
| Molecular Weight | 296.32 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
Related Dimefline Standards
- Dimefline Impurity 2 (CAS CATO-C4X-33512)
- Dimefline Impurity 10 (CAS 95279-60-0)
- Dimefline Impurity 5 (CAS CATO-C4X-33515)
- Dimefline HCl (CAS 1165-48-6)
- Dimefline Impurity 7 (CAS CATO-C4X-33517)
- Dimefline Impurity 9 (CAS CATO-C4X-33519)
- Dimefline Impurity 3 (CAS CATO-C4X-33513)
- Dimefline Impurity 4 (CAS CATO-C4X-33514)
Recommended Standards
- Landiolol Impurity 25 (CAS CATO-C4X-262125)
- 5-carbamoyl-10,11-dihydro-5H-dibenzo[b,f]azepin-10-yl acetate (CAS CATO-C4X-34871)
- Tegoprazan Impurity 4 (CAS CATO-C4X-22974)
- Eslicarbazepine Acetate (CAS 236395-14-5)
- Oclacitinib Impurity 20 (CAS 1312034-36-8)
- Rivaroxaban Impurity 26 (CAS CATO-C4X-109026)
- Vincamine EP Impurity B (CAS 6835-99-0)
- 6-(Benzylamino)-1,3-dimethyl-5-nitropyrimidine-2,4(1H,3H)-dione (CAS 60228-90-2)
- 4-Nitro-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazole-3-carbaldehyde (CAS 518990-08-4)
- Ethyl 2-(7-methoxy-3-methylquinoxalin-2-yl)acetate (CAS 1707371-42-3)
- Mivacurium Chloride Impurity 18 (CAS CATO-C4X-137518)
- Regadenoson Impurity 27 (CAS 89365-25-3)
- 2-Amino-N-(4-methoxyphenyl)-6-(tert-pentyl)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide (CAS 774575-33-6)
- Allo-Thr5-Tirzepatide (CAS CATO-CPTD788934)
Why CATO?
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