1-(2-Chloro-7-fluoroquinolin-3-yl)ethan-1-one CAS 1017463-76-1
| CAS No. | 1017463-76-1 |
| Molecular Formula | C11H7ClFNO |
| Molecular Weight | 223.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 1-(2-Chloro-7-fluoroquinolin-3-yl)ethan-1-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies 1-(2-Chloro-7-fluoroquinolin-3-yl)ethan-1-one (CAS 1017463-76-1), a certified reference material (molecular formula C11H7ClFNO, MW 223.63 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 1-(2-Chloro-7-fluoroquinolin-3-yl)ethan-1-one is typically pale yellow to yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 223.63 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C11H7ClFNO |
| Molecular Weight | 223.63 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 1-(2-Chloro-6-fluoroquinolin-3-yl)ethanone (CAS 1017429-01-4)
- 1-(2-Chloro-8-fluoroquinolin-3-yl)ethanone (CAS 1065481-26-6)
- 5-(4-Chloro-3-fluorophenyl)pyrazin-2-amine (CAS 1069494-45-6)
- 2-Chloro-6-(4-fluorophenoxy)pyridine (CAS 1090916-41-8)
- 6-Chloro-N-(4-fluorophenyl)pyridazin-3-amine (CAS 1094423-93-4)
- 5-(4-Chloro-2-fluorophenyl)pyrimidin-2-amine (CAS 1111111-97-7)
- 2-Chloro-7-fluoro-8-methylquinoline-3-carboxaldehyde (CAS 1167542-21-3)
- 4-(3-Chloro-4-fluorophenyl)pyrimidin-2-amine (CAS 1249713-59-4)
Recommended Standards
- 4-(Chlorosulfonyl)-1-methyl-1h-pyrrole-2-carboxylic acid (CAS 1000932-01-3)
- N-(2-chlorobenzyl)-2,2,2-trifluoroethan-1-amine (CAS 823190-02-9)
- Methyl 7-chloropyrido[2,3-d]pyrimidine-4-carboxylate (CAS 2306277-66-5)
- 7-Amino-6-chloro-1,8-naphthyridine-3-carboxylic acid (CAS 2691878-59-6)
- 2-Bromo-4-carboethoxybenzophenone (CAS 746651-78-5)
- trans,trans-4'-(3-Butenyl)-4-(3,4-difluorophenyl)bicyclohexyl (CAS 155266-68-5)
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- 2-Ethoxy-6-(trifluoromethyl)pyridine (CAS 1245563-18-1)
- Isoindolin-5-ylmethanamine (CAS 910292-33-0)
- tert-Butyl 3-(1-iodoethyl)azetidine-1-carboxylate (CAS 1420881-44-2)
- N-((2-phenylthiazol-5-yl)methyl)ethanamine (CAS 886494-12-8)
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