4-Ethoxy-3,5-difluorobenzoyl chloride CAS 1017779-21-3
| CAS No. | 1017779-21-3 |
| Molecular Formula | C9H7ClF2O2 |
| Molecular Weight | 220.60 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 4-Ethoxy-3,5-difluorobenzoyl chloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
4-Ethoxy-3,5-difluorobenzoyl chloride (CAS 1017779-21-3), molecular formula C9H7ClF2O2 and molecular weight 220.60 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system, 4-Ethoxy-3,5-difluorobenzoyl chloride is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 220.60 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C9H7ClF2O2 |
| Molecular Weight | 220.60 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F/Cl-containing |
Related Ethoxy Standards
- 2-Ethoxy-3,5-difluorobenzoyl chloride (CAS 1017779-72-4)
- 3-Ethoxy-2,4-difluorobenzoyl chloride (CAS 1017779-90-6)
- 3-Ethoxy-2,6-difluorobenzoyl chloride (CAS 1092461-27-2)
- 4-Ethoxy-2,6-difluorobenzoyl chloride (CAS 1373920-79-6)
- 4-Ethoxy-2,3-difluorobenzoyl chloride (CAS 761459-04-5)
- (8-Ethoxy-1-methyl-1,2,3,4-tetrahydroquinolin-3-yl)methanamine (CAS 1502058-65-2)
- 1-(4-Ethoxy-2-methylphenyl)piperazine (CAS 817170-68-6)
- 4-Ethoxy-2-propyl-3,4-dihydro-2H-pyrido[1,2-a]pyrimidine (CAS 210159-52-7)
Recommended Standards
- Dimethyl (4-chlorophenyl)phosphonate (CAS 13114-07-3)
- 1-(2-Chloropropanoyl)-5-fluoropyrimidine-2,4(1H,3H)-dione (CAS 110073-44-4)
- Chlorodimethyl(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)silane (CAS 929887-16-1)
- 8-Chloro-6-(trifluoromethyl)imidazo[1,5-a]pyridine (CAS 2064217-67-8)
- 11-Methyl-13-(3-methylphenyl)-1,8-diazatricyclo[7.4.0.0,2,7]trideca-2,4,6,8,10,12-hexaene-10-carbonitrile (CAS 730976-50-8)
- SR 13668, 97% (CAS 637774-61-9)
- 2-Fluoro-6-(1H-pyrazol-4-yl)aniline (CAS 1820666-38-3)
- 4-[(3-Chlorophenyl)methoxy]-6-{[(4-chlorophenyl)sulfanyl]methyl}-2-methylpyrimidine (CAS 338960-41-1)
- Methyl 5-bromo-2-(methylthio)benzoate (CAS 929000-14-6)
- 2-(4-Iodophenoxy)benzaldehyde (CAS 262444-19-9)
- 3-Hydroxy-4-(methylthio)benzoic acid (CAS 1243282-54-3)
- 1-(6-(Methylsulfonyl)pyrimidin-4-yl)piperidine-4-carboxylic acid (CAS 1707594-81-7)
- Lexacalcitol (CAS 131875-08-6)
- Neuropeptide S (rat) (CAS 412938-75-1)
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