Tert-butyl 4-(5-bromonicotinoyl)piperazine-1-carboxylate CAS 1017782-72-7
| CAS No. | 1017782-72-7 |
| Molecular Formula | C15H20BrN3O3 |
| Molecular Weight | 370.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Tert-butyl 4-(5-bromonicotinoyl)piperazine-1-carboxylate (C15H20BrN3O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Tert-butyl 4-(5-bromonicotinoyl)piperazine-1-carboxylate (CAS 1017782-72-7) is a high-purity analytical reference standard with the molecular formula C15H20BrN3O3 and a molecular weight of 370.24 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures Tert-butyl 4-(5-bromonicotinoyl)piperazine-1-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H20BrN3O3 |
| Molecular Weight | 370.24 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 3 |
Recommended Standards
- Felodipine Impurity 11 (CAS 150131-21-8)
- N-(5-(5-Bromothiophen-2-yl)-1,3,4-oxadiazol-2-yl)-2-(thiophen-2-yl)acetamide (CAS 1021105-27-0)
- Felodipine EP Impurity B (CAS 91189-59-2)
- Methyl2-(4-bromophenyl)-1-((tert-Butoxycarbonyl)amino)cyclopropane-1-carboxylate (CAS 1092460-42-8)
- 2-Bromo-5-(4-fluorophenyl)-1,3,4-oxadiazole (CAS 926240-17-7)
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- 1,3-Oxazolidine-2-thione (CAS 5840-81-3)
- Semaglutide impurity 29 (CAS 1188328-22-4)
Why CATO?
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