5,7-Dimethyl-2-(methylthio)pyrazolo[1,5-a]pyrimidine-3-carboxylic acid CAS 1018046-46-2
| CAS No. | 1018046-46-2 |
| Molecular Formula | C10H11N3O2S |
| Molecular Weight | 237.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 5,7-Dimethyl-2-(methylthio)pyrazolo[1,5-a]pyrimidine-3-carboxylic acid (CAS 1018046-46-2), a certified reference material (molecular formula C10H11N3O2S, MW 237.28 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, 5,7-Dimethyl-2-(methylthio)pyrazolo[1,5-a]pyrimidine-3-carboxylic acid is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 237.28 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H11N3O2S |
| Molecular Weight | 237.28 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Dimethyl Standards
- 2-(2-(3,5-Dimethyl-1H-pyrazol-1-yl)thiazol-4-yl)acetic acid (CAS 1177209-02-7)
- 2-((5,7-Dimethyl-[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)thio)acetamide (CAS 74537-92-1)
- 2-((6,9-Dimethyl-9H-purin-2-yl)thio)acetamide (CAS 52379-96-1)
- 2,5-Dimethyl-1-[(oxan-3-yl)methyl]-1h-pyrrole-3-carboxylic acid (CAS 1292222-06-0)
- 5-(3,5-Dimethyl-isoxazol-4-ylmethyl)-thiophene-2-carboxylic acid (CAS 878713-69-0)
- 1-[(1,5-dimethyl-1h-pyrazol-4-yl)methyl]piperidine-4-carboxylic acid (CAS 1006483-68-6)
- 1-[(1,5-dimethyl-1h-pyrazol-4-yl)methyl]piperidine-3-carboxylic acid (CAS 1006483-78-8)
- 3-[4-(2,5-Dimethyl-1H-pyrrol-1-yl)phenyl]-1H-pyrazole (CAS 1007014-32-5)
Recommended Standards
- Ethyl n-(6-amino-1,3-benzothiazol-2-yl)carbamate (CAS 1016526-95-6)
- 5-((2-Methoxyphenoxy)methyl)-1,3,4-thiadiazol-2-amine (CAS 1018474-87-7)
- 2-(((5-Methylisoxazol-3-yl)methyl)thio)pyrimidine-4,6-diamine (CAS 1003769-00-3)
- 4-(Dimethylamino)-5-methylthieno[2,3-d]pyrimidine-6-carboxylic acid (CAS 1082147-20-3)
- N-(tert-butyl)-2-((4-methyl-5-(pyrazin-2-yl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 731788-61-7)
- 4-(Tetrahydro-2H-pyran-4-yl)methoxyphenylboronic acid (CAS 1615247-95-4)
- (1r,1's,4R,4'R)-4-(3-fluoro-4-(trifluoromethoxy)phenyl)-4'-propyl-1,1'-bi(cyclohexane) (CAS 137810-19-6)
- 6-Methyl-2,3-dihydrobenzofuran-3-acetic Acid (CAS 1221498-01-6)
- N-(2,3,4,9-tetrahydro-1H-carbazol-1-ylidene)hydroxylamine (CAS 91391-94-5)
- 4-Chloro-1-(3-chloro-2-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidine (CAS 1207832-97-0)
- Finasteride Impurity 55 (CAS CATO-C4X-164555)
- 3-(3,5-Dimethylphenyl)-2-(methylthio)-6,7-dihydrothieno[3,2-d]pyrimidin-4(3H)-one (CAS 877653-19-5)
- 2-Methyl-2-(4-nitrophenyl)-1,3-dioxolane (CAS 19073-15-5)
- Hepcidin/LEAP-1 (Human); Liver-Expressed Antimicrobial Peptide (CAS 342790-21-0)
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