Methyl 2-(4-(difluoromethyl)-3-methyl-6-oxo-1-phenyl-1H-pyrazolo[3,4-b]pyridin-7(6H)-yl)acetate CAS 1018052-31-7
| CAS No. | 1018052-31-7 |
| Molecular Formula | C17H15F2N3O3 |
| Molecular Weight | 347.32 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Methyl 2-(4-(difluoromethyl)-3-methyl-6-oxo-1-phenyl-1H-pyrazolo[3,4-b]pyridin-7(6H)-yl)acetate.
Methyl 2-(4-(difluoromethyl)-3-methyl-6-oxo-1-phenyl-1H-pyrazolo[3,4-b]pyridin-7(6H)-yl)acetate (CAS 1018052-31-7) is a high-purity analytical reference standard with the molecular formula C17H15F2N3O3 and a molecular weight of 347.32 g/mol.
Methyl 2-(4-(difluoromethyl)-3-methyl-6-oxo-1-phenyl-1H-pyrazolo[3,4-b]pyridin-7(6H)-yl)acetate (C17H15F2N3O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures Methyl 2-(4-(difluoromethyl)-3-methyl-6-oxo-1-phenyl-1H-pyrazolo[3,4-b]pyridin-7(6H)-yl)acetate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H15F2N3O3 |
| Molecular Weight | 347.32 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Methyl Standards
- 3-(2-Benzyl-4-(difluoromethyl)-6-oxo-2,6-dihydro-7H-pyrazolo[3,4-b]pyridin-7-yl)propanoic acid (CAS 1018127-17-7)
- 2-[4-(difluoromethyl)-6-(3-methoxyphenyl)-3-methyl-1h-pyrazolo[3,4-b]pyridin-1-yl]acetic acid (CAS 937607-17-5)
- 2-[4-(difluoromethyl)-6-(4-methoxyphenyl)-3-methyl-1h-pyrazolo[3,4-b]pyridin-1-yl]acetic acid (CAS 937607-18-6)
- Ethyl 7-(difluoromethyl)-5-(2-methoxyphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxylate (CAS 754230-33-6)
- Ethyl 7-(difluoromethyl)-5-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxylate (CAS 492433-50-8)
- N-(4-((Difluoromethyl)thio)phenyl)-2-oxo-2H-chromene-3-carboxamide (CAS 578751-68-5)
- 2-(Difluoromethyl)-4-iodo-3-methoxypyridine-5-carbonyl chloride (CAS 1805073-09-9)
- 2-(Difluoromethyl)-6-iodo-3-methoxypyridine-4-carbonyl chloride (CAS 1805073-27-1)
Recommended Standards
- Methyl 6-(4-(difluoromethoxy)phenyl)-1,3-dimethyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylate (CAS 1011397-96-8)
- 2-[3-cyclopropyl-4-(difluoromethyl)-6-(1-methyl-1h-pyrazol-4-yl)-1h-pyrazolo[3,4-b]pyridin-1-yl]acetic acid (CAS 1006445-08-4)
- 2-[3-cyclopropyl-4-(difluoromethyl)-6-(1-methyl-1h-pyrazol-3-yl)-1h-pyrazolo[3,4-b]pyridin-1-yl]acetic acid (CAS 1170416-36-0)
- Ethyl N-(2-{[3-cyano-6-methyl-4-(trifluoromethyl)pyridin-2-yl]sulfanyl}acetyl)carbamate (CAS 625376-47-8)
- 2-(4-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)acetic acid (CAS 1424081-43-5)
- 2,2-dicyclopentyl-2-(pyridin-4-yl)acetonitrile (CAS 1955554-06-9)
- N-((4aR,6R,7R,8R,8aS)-8-hydroxy-6-methoxy-2-phenylhexahydropyrano[3,2-d][1,3]dioxin-7-yl)acetamide (CAS 10300-76-2)
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- 4-(3,4-Dihydroisoquinolin-2(1H)-yl)butan-1-amine (CAS 174643-96-0)
- 3-Bromo-2-fluoro-5-iodobenzoic acid (CAS 1992023-57-0)
- 1-[(4-Methoxyphenyl)methyl]-3-methyl-4-[4-(propan-2-yl)phenyl]-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 860785-35-9)
- 1-Isobutyl-3-(thiophen-3-yl)-1H-pyrazole-4-carboxylic acid (CAS 1456003-02-3)
- [β-Asp]9-Semaglutide (CAS CATO-CPTD788605)
Why CATO?
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