3-(2-Cyclopentyl-6-oxo-4-(trifluoromethyl)-2,6-dihydro-7h-pyrazolo[3,4-b]pyridin-7-yl)propanoic acid CAS 1018127-13-3
| CAS No. | 1018127-13-3 |
| Molecular Formula | C15H16F3N3O3 |
| Molecular Weight | 343.30 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-(2-Cyclopentyl-6-oxo-4-(trifluoromethyl)-2,6-dihydro-7h-pyrazolo[3,4-b]pyridin-7-yl)propanoic acid is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
3-(2-Cyclopentyl-6-oxo-4-(trifluoromethyl)-2,6-dihydro-7h-pyrazolo[3,4-b]pyridin-7-yl)propanoic acid (CAS 1018127-13-3), molecular formula C15H16F3N3O3 and molecular weight 343.30 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-(2-Cyclopentyl-6-oxo-4-(trifluoromethyl)-2,6-dihydro-7h-pyrazolo[3,4-b]pyridin-7-yl)propanoic acid (C15H16F3N3O3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 3-(2-Cyclopentyl-6-oxo-4-(trifluoromethyl)-2,6-dihydro-7h-pyrazolo[3,4-b]pyridin-7-yl)propanoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H16F3N3O3 |
| Molecular Weight | 343.30 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Cyclopentyl Standards
- 3-Cyclopentyl-7-((thiophen-2-ylmethyl)amino)pyrimido[4,5-d]pyrimidine-2,4(1H,3H)-dione (CAS 1396810-30-2)
- 3-Cyclopentyl-1-({1-[4-methyl-2-(pyridin-3-yl)-1,3-thiazol-5-yl]ethylidene}amino)urea (CAS 1356819-44-7)
- 1383539-73-8 4-cyclopentyl-2-[[(2,5-dimethylphenyl)methyl]thio]-1,6-dihydro-6-oxo-5-pyrimidinecarbonitrile (CAS 1383539-73-8)
- 3-Cyclopentyl-N-(2-(1-propyl-1,2,3,4-tetrahydroquinolin-6-yl)ethyl)propanamide (CAS 955527-47-6)
- N-Cyclopentyl-2-(2-(3-phenylureido)thiazol-4-yl)acetamide (CAS 946325-09-3)
- 1-((1-Cyclopentyl-4,5,6,7-tetrahydro-1H-indazol-3-yl)methyl)-3-(thiophen-2-yl)urea (CAS 1448078-55-4)
- 1-Cyclopentyl-4-iodo-5-(trifluoromethyl)-1H-pyrazol-3-amine (CAS 1354704-19-0)
- N-Cyclopentyl-5-ethyl-11-oxo-5H,5aH,6H,7H,8H,9H,11H-pyrido[2,1-b]quinazoline-3-carboxamide (CAS 1574595-90-6)
Recommended Standards
- Cinitapride impurity 6 (CAS CATO-C4X-29086)
- 5-(tert-Butyloxycarbonyamino)methyl-3-(4-(trifluoromethyl)phenyl)-[1,2,4]oxadiazole (CAS 1053656-56-6)
- 2H-1,4-Benzoxazin-3(4H)-one, 2-(β-D-glucopyranosyloxy)-4-hydroxy- (CAS 22260-47-5)
- 2-tert-Butyloxycarbonylaminomethyl-5-(4-(trifluoromethyl)phenyl)-[1,3,4]oxadiazole (CAS 1053656-77-1)
- 1-Oxo-1,2-dihydroisoquinoline-4-carbonitrile (CAS 53000-96-7)
- Tris(2-ethylhexyl)citrate (CAS 7147-34-4)
- 1-isopropyl-3-methyl-1H-pyrazol-4-amine,HCl (CAS 1257554-91-8)
- 5-Methyl-2-(pyridin-2-yl)indoline (CAS 595547-86-7)
- 4-Amino-5-[3-(4-methoxyphenyl)-1h-pyrazol-5-yl]-4h-1,2,4-triazole-3-thiol (CAS 1032282-87-3)
- (2-(Cyclohexylamino)phenyl)diphenylphosphineoxide (CAS 98821-89-7)
- 2-(2-Methoxy-5-methylphenyl)propanenitrile (CAS 1082496-38-5)
- 5-[4-(diethylamino)phenyl]-4-(2-methylphenyl)-2,4-dihydro-3H-1,2,4-triazole-3-thione (CAS 851207-79-9)
- N-(Cyclopropylmethyl)-2,3-dihydrobenzofuran-5-amine (CAS 61090-73-1)
- Fibrinogen Related Peptide (CAS 80755-86-8)
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