Methyl 1-(2-cyanoethyl)-6-(4-fluorophenyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylate CAS 1018142-10-3
| CAS No. | 1018142-10-3 |
| Molecular Formula | C18H15FN4O2 |
| Molecular Weight | 338.34 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Methyl 1-(2-cyanoethyl)-6-(4-fluorophenyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylate (CAS 1018142-10-3), molecular formula C18H15FN4O2 and molecular weight 338.34 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Methyl 1-(2-cyanoethyl)-6-(4-fluorophenyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylate (C18H15FN4O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H15FN4O2 |
| Molecular Weight | 338.34 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Methyl Standards
- N-(2-Cyanoethyl)-2,2-Difluoro-N-Methyl-6-Nitrochromene-4-Carbothioamide (CAS 152661-13-7)
- 2-[(2-Cyanoethyl)sulfanyl]-6-(5-methylfuran-2-yl)-4-(trifluoromethyl)pyridine-3-carbonitrile (CAS 625376-80-9)
- N-(1-cyanoethyl)-2-(2,6-dioxo-3-piperidyl)-1-oxo-isoindoline-5-carboxamide (CAS 2629201-62-1)
- 6-(N-(2-cyanoethyl)-N-methylsulfamoyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (CAS 317329-41-2)
- Methyl 1-(2-cyanoethyl)-6-(4-methoxyphenyl)-3-methyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylate (CAS 1018051-61-0)
- 3'-(2-Cyanoethyl) 5'-ethyl 2',6'-dimethyl-[3,4'-bipyridine]-3',5'-dicarboxylate (CAS 87966-46-9)
- Methyl 1-(2-cyanoethyl)-3-methyl-6-(pyridin-3-yl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylate (CAS 1018051-04-1)
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Recommended Standards
- Linezolid Impurity 4 (CAS 496031-56-2)
- 1-(3-Fluorobenzyl)-N-(3-methylpyridin-2-yl)-6-oxo-1,6-dihydropyridazine-3-carboxamide (CAS 1040664-11-6)
- trimethyl-[2-[[4-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazol-1-yl]methoxy]ethyl]silane (CAS 2780325-20-2)
- 2-(3-(3-Fluorophenyl)ureido)-N-(quinolin-8-yl)acetamide (CAS 1252435-26-9)
- 3-Fluoro-2-methoxy-5-sulfamoylbenzoic acid (CAS 1375474-71-7)
- 4-(4-tert-Butylbenzoyl)-1H-pyrrole-2-carboxylic acid (CAS 439111-53-2)
- 2-Amino-4-guanidinobutanoic acid hydrochloride (CAS 87876-04-8)
- (S)-Benzyl (4-hydroxybutan-2-yl)carbamate (CAS 168827-91-6)
- Minoxidil Impurity 37 (CAS 55034-35-0)
- 4-(2,4-Dimethylphenyl)-5-methylthiazol-2-amine (CAS 438227-56-6)
- 9-Bromo-10-(9-phenanthryl)anthracene (CAS 845457-53-6)
- Bumetrizole (CAS 3896-11-5)
- 2-((4-Amino-5-(3-methoxyphenyl)-4H-1,2,4-triazol-3-yl)thio)-N-(2,6-dimethylphenyl)acetamide (CAS 763114-89-2)
- Semaglutide impurity 193 (CAS CATO-C4X-2226193)
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