4-(Difluoromethyl)-2-isobutyl-2h-pyrazolo[3,4-b]pyridin-6-ol CAS 1018163-68-2

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-(Difluoromethyl)-2-isobutyl-2h-pyrazolo[3,4-b]pyridin-6-ol.

4-(Difluoromethyl)-2-isobutyl-2h-pyrazolo[3,4-b]pyridin-6-ol (CAS 1018163-68-2), molecular formula C11H13F2N3O and molecular weight 241.24 g/mol, is a CATO reference standard with documented purity and traceability.

4-(Difluoromethyl)-2-isobutyl-2h-pyrazolo[3,4-b]pyridin-6-ol (C11H13F2N3O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 4-(Difluoromethyl)-2-isobutyl-2h-pyrazolo[3,4-b]pyridin-6-ol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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