(E)-2-Cyano-3-(3,4-difluorophenyl)but-2-enamide CAS 1018166-49-8

Purity 97%+In StockPharmaceutical Standards
CAS No.1018166-49-8
Molecular FormulaC11H8F2N2O
Molecular Weight222.19 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(E)-2-Cyano-3-(3,4-difluorophenyl)but-2-enamide CAS 1018166-49-8 chemical structure

Description

The occurrence of (E)-2-Cyano-3-(3,4-difluorophenyl)but-2-enamide is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies (E)-2-Cyano-3-(3,4-difluorophenyl)but-2-enamide (CAS 1018166-49-8), a certified reference material (molecular formula C11H8F2N2O, MW 222.19 g/mol) for analytical method development and quality control.

(E)-2-Cyano-3-(3,4-difluorophenyl)but-2-enamide (C11H8F2N2O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.

As a certified reference material (CRM), (E)-2-Cyano-3-(3,4-difluorophenyl)but-2-enamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC11H8F2N2O
Molecular Weight222.19 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1988
Halogen ContentF-containing
Nitrogen Atoms2

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