6-Chloro-2-cyclopentyl-4-(difluoromethyl)-2h-pyrazolo[3,4-b]pyridine CAS 1018166-86-3
| CAS No. | 1018166-86-3 |
| Molecular Formula | C12H12ClF2N3 |
| Molecular Weight | 271.69 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
6-Chloro-2-cyclopentyl-4-(difluoromethyl)-2h-pyrazolo[3,4-b]pyridine (CAS 1018166-86-3), molecular formula C12H12ClF2N3 and molecular weight 271.69 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 6-Chloro-2-cyclopentyl-4-(difluoromethyl)-2h-pyrazolo[3,4-b]pyridine (C12H12ClF2N3) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures 6-Chloro-2-cyclopentyl-4-(difluoromethyl)-2h-pyrazolo[3,4-b]pyridine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H12ClF2N3 |
| Molecular Weight | 271.69 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
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Why CATO?
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