3-Amino-4-chloro-N-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)benzamide CAS 1018245-57-2
| CAS No. | 1018245-57-2 |
| Molecular Formula | C15H13ClN2O3 |
| Molecular Weight | 304.73 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-Amino-4-chloro-N-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)benzamide is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 3-Amino-4-chloro-N-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)benzamide (CAS 1018245-57-2), a certified reference material (molecular formula C15H13ClN2O3, MW 304.73 g/mol) for analytical method development and quality control.
3-Amino-4-chloro-N-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)benzamide (C15H13ClN2O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-Amino-4-chloro-N-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)benzamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H13ClN2O3 |
| Molecular Weight | 304.73 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Amino Standards
- 4-Amino-2-chloro-N-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)benzamide (CAS 1018247-50-1)
- 5-amino-N-(2H-1,3-benzodioxol-5-ylmethyl)-2-chlorobenzamide (CAS 1018269-73-2)
- 2-amino-N-(2H-1,3-benzodioxol-5-ylmethyl)-6-chlorobenzamide (CAS 1411540-92-5)
- N-(2-Amino-5-chloro-a-phenylbenzylidene)glycine N-oxide (CAS 793-99-7)
- 3-Amino-4-(3-chlorophenyl)-1-(4-fluorobenzyl)azetidin-2-one (CAS 1291488-13-5)
- N-(3-Amino-4-chlorophenyl)-2-(4-ethylphenoxy)-acetamide (CAS 1020054-52-7)
- N-(3-Amino-4-chlorophenyl)-2-(4-methylphenoxy)-propanamide (CAS 1020054-60-7)
- N-(3-Amino-4-chlorophenyl)-2-(3,4-dimethylphenoxy)acetamide (CAS 1020054-63-0)
Recommended Standards
- Isopropenyloxytris(trimethylsilyl)silane (CAS 861869-12-7)
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- 8-(2-Chloro-4,5-difluorophenyl)-8-oxooctanoic acid (CAS 951891-55-7)
- 2-Chloro-N-(2-methyl-5-nitrophenyl)-2-phenylacetamide (CAS 1098355-79-3)
- 3-Fluoro-4-methylpicolinic acid (CAS 1211587-40-4)
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- 3-[(4-fluoro-3-methylphenyl)carbonyl]pyridine (CAS 1182940-73-3)
- 6-Chloropyrazolo[1,5-a]pyridin-5-amine (CAS 1951428-41-3)
- 3-thien-2-yl[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-amine (CAS 80809-42-3)
- 1-(2'-Methyl[1,1'-biphenyl]-2-yl)ethanone (CAS 217468-51-4)
- 1-(4-Methoxyphenyl)-3-methyl-1H-pyrazol-5(4H)-one (CAS 60798-06-3)
- (3-(Dimethylamino)propyl)triphenylphosphonium (CAS 89207-40-9)
- 6-Phenyl-1H,2H,3H-pyrazolo[1,5-a]imidazole (CAS 1526060-01-4)
- Allo-D-Ile17-Tirzepatide (CAS CATO-CPTD788962)
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