2-(3-Ethoxy-4-methoxyphenyl)-1H-benzimidazole-5-carboxylic acid CAS 1018255-95-2
| CAS No. | 1018255-95-2 |
| Molecular Formula | C17H16N2O4 |
| Molecular Weight | 312.32 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2-(3-Ethoxy-4-methoxyphenyl)-1H-benzimidazole-5-carboxylic acid (C17H16N2O4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies 2-(3-Ethoxy-4-methoxyphenyl)-1H-benzimidazole-5-carboxylic acid (CAS 1018255-95-2), a certified reference material (molecular formula C17H16N2O4, MW 312.32 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H16N2O4 |
| Molecular Weight | 312.32 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Nitrogen Atoms | 2 |
Related Ethoxy Standards
- 2-(4-Ethoxy-3-methoxyphenyl)-1H-benzo[d]imidazole-6-carboxylic acid (CAS 1018300-85-0)
- Methyl 2-(3-ethoxy-4-hydroxyphenyl)-1H-benzo[d]imidazole-6-carboxylate (CAS 1416347-62-0)
- 5-Ethoxy-2-(4-(4-fluorophenyl)-5-methyl-1H-pyrazol-3-yl)phenol (CAS 394237-59-3)
- N-(2-Ethoxy-4-nitrophenyl)phthalimide (CAS 106981-60-6)
- Ethyl 4-[3-(2-ethoxy-2-oxoethyl)phenyl]benzoate (CAS 1375068-97-5)
- 1-Ethoxy-2,3-difluoro-4-(((1s,4r)-4-propylcyclohexyl)methoxy)benzene (CAS 875468-59-0)
- 1-((2-Ethoxy-4,5-dimethylphenyl)sulfonyl)azepane (CAS 898646-78-1)
- 2-Ethoxy-N-((3-methyl-1,2,4-oxadiazol-5-yl)methyl)-1-naphthamide (CAS 1235284-04-4)
Recommended Standards
- 6-Isopropyl-3-(3-methoxyphenyl)isoxazolo[5,4-b]pyridine-4-carboxylic acid (CAS 1018127-33-7)
- XAV-939 (CAS 284028-89-3)
- N-(tert-Butoxycarbonyl)-D-proline Succinimidyl Ester (CAS 102185-34-2)
- Ethyl 2-((3-methoxypropyl)imino)-4-(trifluoromethyl)-2,3-dihydrothiazole-5-carboxylate (CAS 937597-98-3)
- 8-methoxy-5-methyl-1,2,3,4-tetrahydroquinoline (CAS 953726-89-1)
- n-(2-Chlorophenyl)-2-(methylamino)acetamide (CAS 731827-18-2)
- 6-Chloro-3-methyl-1-phenyl-1H-indole (CAS 918163-13-0)
- n-(Benzo[d][1,3]dioxol-5-ylmethyl)pyrazin-2-amine (CAS 930859-14-6)
- 5-Cyclopropyl-1-(cyclopropylmethyl)-1h-1,2,3-triazole-4-carboxylic acid (CAS 1249186-63-7)
- 6-Bromo-3-iodo-2-methoxypyridine (CAS 1310949-37-1)
- 5-Chloro-1H-pyrrole-2-carbaldehyde (CAS 1757-28-4)
- Ethyl 4-(3-fluorophenyl)thiazole-2-carboxylate (CAS 886366-78-5)
- propan-2-yl (2S)-2-amino-3-(4-hydroxyphenyl)propanoate hydrochloride (CAS 38589-95-6)
- Tirzepatide Impurity 23 X TFA Salt (CAS CATO-C4X-324023)
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