1-(7-Bromo-1H-indol-3-yl)-2-chloroethan-1-one CAS 1018593-32-2
| CAS No. | 1018593-32-2 |
| Molecular Formula | C10H7BrClNO |
| Molecular Weight | 272.53 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(7-Bromo-1H-indol-3-yl)-2-chloroethan-1-one.
1-(7-Bromo-1H-indol-3-yl)-2-chloroethan-1-one (CAS 1018593-32-2), molecular formula C10H7BrClNO and molecular weight 272.53 g/mol, is a CATO reference standard with documented purity and traceability.
1-(7-Bromo-1H-indol-3-yl)-2-chloroethan-1-one (C10H7BrClNO) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine/bromine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 1-(7-Bromo-1H-indol-3-yl)-2-chloroethan-1-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H7BrClNO |
| Molecular Weight | 272.53 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
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