6-Bromo-8-fluoro-4-hydroxyquinoline-3-carboxylic acid CAS 1019016-07-9
| CAS No. | 1019016-07-9 |
| Molecular Formula | C10H5BrFNO3 |
| Molecular Weight | 286.05 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6-Bromo-8-fluoro-4-hydroxyquinoline-3-carboxylic acid.
6-Bromo-8-fluoro-4-hydroxyquinoline-3-carboxylic acid (CAS 1019016-07-9), molecular formula C10H5BrFNO3 and molecular weight 286.05 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution, 6-Bromo-8-fluoro-4-hydroxyquinoline-3-carboxylic acid is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 286.05 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H5BrFNO3 |
| Molecular Weight | 286.05 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
- 8-Bromo-6-fluoro-4-hydroxyquinoline-3-carboxylic acid (CAS 1019016-15-9)
- 8-Bromo-5-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (CAS 1065093-62-0)
- 5-Bromo-8-fluoro-4-hydroxyquinoline-3-carboxylic acid (CAS 1065093-65-3)
- 3-(4-Bromo-2-fluorophenyl)isoxazole-5-carboxylic acid (CAS 1099629-55-6)
- 3-(5-Bromo-2-fluorophenyl)isoxazole-5-carboxylic acid (CAS 1126636-69-8)
- 3-(3-Bromo-4-fluorophenyl)isoxazole-5-carboxylic acid (CAS 1152531-69-5)
- 2-(4-Bromo-7-fluoro-3-indolyl)-2-oxoacetic Acid (CAS 1154742-87-6)
- 3-Bromo-2,4-dimethoxy-6-(trifluoromethyl)pyridine (CAS 1214345-77-3)
Recommended Standards
- GenX E1 (CAS 3330-15-2)
- 8-Bromo-6-nitroquinazoline-2,4-diol (CAS 309295-31-6)
- 7-Bromo-5-nitrobenzofuran-2-carboxylic acid (CAS 286836-15-5)
- 5-Bromo-4-nitro-1H-indazole-3-carboxylic acid (CAS 865886-79-9)
- Thieno[3,2-c]pyridazine (CAS 22390-25-6)
- ((1R,7a'S)-2,2-Difluorodihydro-1'H,3'H-spiro[cyclopropane-1,2'-pyrrolizin]-7a'(5'H)-yl)methanol (CAS 2850327-37-4)
- 4,4-Difluoro-1-[(2-fluorophenyl)methyl]cyclohexane-1-carboxylic acid (CAS 1389313-48-7)
- propyl 2-cyanopentanoate (CAS CATO-C4X-116658)
- 3-Acetoxy-3,4-dimethylbenzophenone (CAS 890099-17-9)
- Empagliflozin Impurity 315 (CAS CATO-C4X-1065315)
- 2-Bromo-3-(4-fluorophenyl)-1-propene (CAS 731773-10-7)
- 4-(chloromethyl)thiazole (CAS 3364-76-9)
- Vinpocetine Impurity 20 (CAS 38990-16-8)
- Semaglutide impurity 269 (CAS CATO-C4X-2226269)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com