Pioglitazone Impurity 02 CAS 101931-00-4
| CAS No. | 101931-00-4 |
| Molecular Formula | C19H20N2O4S |
| Molecular Weight | 372.44 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Pioglitazone Impurity 02 (C19H20N2O4S) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a process- or degradation-related impurity, Pioglitazone Impurity 02 (CAS 101931-00-4, C19H20N2O4S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Pioglitazone Impurity 02 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H20N2O4S |
| Molecular Weight | 372.44 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Pioglitazone Standards
- Pioglitazone (CAS 625853-74-9)
- Pioglitazone impurity 62 (CAS CATO-C4X-138362)
- Pioglitazone N-Oxide (CAS 145350-09-0)
- Pioglitazone Didehydro Hydroxy Impurity (CAS 646519-84-8)
- Pioglitazone Ketone (M-III) (CAS 146062-45-5)
- Pioglitazone impurity 27 (CAS CATO-C4X-138327)
- Pioglitazone impurity 37 (CAS CATO-C4X-138337)
- Pioglitazone impurity 51 (CAS CATO-C4X-138351)
Recommended Standards
- 3-(4-methanesulfonylphenyl)-N-(oxan-4-yl)imidazo[1,2-b]pyridazin-6-amine (CAS 1012345-16-2)
- 1020722-07-9 3-(tert-Butoxycarbonylamino)-1-(phenylsulfonyl)indole 7565AC C19H20N2O4S (CAS 1020722-07-9)
- 4-{[(1-Methyl-1H-pyrazol-4-yl)methyl][2-(pyrrolidin-1-ylsulfonyl)ethyl]amino}-4-oxobutanoic acid (CAS 1010866-76-8)
- 1020722-09-1 2-(tert-Butoxycarbonylamino)-1-(phenylsulfonyl)indole 7567AC C19H20N2O4S (CAS 1020722-09-1)
- Testosterone Impurity 19 (CAS 2243-06-3)
- Tacrolimus Impurity 26 (CAS 1260758-24-4)
- Ibuprofen EP Impurity G (CAS 2575516-43-5)
- 2-Phenyl-1-(1H-tetrazol-5-yl)ethanamine (CAS 31603-06-2)
- 2-Methoxy-N-(3-methoxy-4-(2-oxopyrrolidin-1-yl)phenyl)acetamide (CAS 922950-02-5)
- Lamivudine Impurity 34 (CAS 389128-28-3)
- N-([1,1'-biphenyl]-4-yl)-9-phenyl-9H-carbazol-3-amine (CAS 1002762-60-8)
- 1-(2-Cyanoethyl)-3-(1-(4-methoxyphenyl)-5-oxopyrrolidin-3-yl)-1-methylurea (CAS 877640-27-2)
- 4-Bromo-1-(phenoxymethyl)-1H-pyrazole (CAS 1263210-93-0)
- D-Tyr1-Tirzepatide (CAS CATO-CPTD788928)
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