4-Methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoyl chloride CAS 1019327-29-7
| CAS No. | 1019327-29-7 |
| Molecular Formula | C14H18BClO3 |
| Molecular Weight | 280.55 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-Methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoyl chloride is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
4-Methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoyl chloride (CAS 1019327-29-7) is a high-purity analytical reference standard with the molecular formula C14H18BClO3 and a molecular weight of 280.55 g/mol.
The molecular framework of 4-Methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoyl chloride (C14H18BClO3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H18BClO3 |
| Molecular Weight | 280.55 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | Cl-containing |
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Recommended Standards
- 312624-15-0 1-Adamantylzinc bromide, 0.5M in THF, packaged under Argon in resealable ChemSeal bottles MFCD00671988 (CAS 312624-15-0)
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- Methyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-1-acetate (CAS 959585-44-5)
- ((2S,5R)-5-(6-(Ethylamino)-9H-purin-9-yl)tetrahydrofuran-2-yl)methanol (CAS 120503-35-7)
- Lydicamycin (CAS 133352-27-9)
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- (2Z)-3-(Dimethylamino)-2-methanesulfonyl-1-(4-methoxyphenyl)prop-2-en-1-one (CAS 344275-61-2)
- Methyl 2-(o-tolyl)pyrimidine-5-carboxylate (CAS 1263059-48-8)
- Peptide Impurity 04 (CAS 2913424-91-4)
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