N-(3-CHloro-4-methylphenyl)-4-hydroxybenzamide CAS 1019378-55-2

Description

Compared with other compounds in its class, the molecular weight of 261.70 g/mol gives N-(3-CHloro-4-methylphenyl)-4-hydroxybenzamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

N-(3-CHloro-4-methylphenyl)-4-hydroxybenzamide (CAS 1019378-55-2) is a high-purity analytical reference standard with the molecular formula C14H12ClNO2 and a molecular weight of 261.70 g/mol.

The molecular framework of N-(3-CHloro-4-methylphenyl)-4-hydroxybenzamide (C14H12ClNO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), N-(3-CHloro-4-methylphenyl)-4-hydroxybenzamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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