4-(butan-2-ylsulfanyl)-2-(trifluoromethyl)aniline CAS 1019539-28-6
| CAS No. | 1019539-28-6 |
| Molecular Formula | C11H14F3NS |
| Molecular Weight | 249.30 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-(butan-2-ylsulfanyl)-2-(trifluoromethyl)aniline (CAS 1019539-28-6), molecular formula C11H14F3NS and molecular weight 249.30 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-(butan-2-ylsulfanyl)-2-(trifluoromethyl)aniline (C11H14F3NS) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H14F3NS |
| Molecular Weight | 249.30 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related butan Standards
- 3-(Butan-2-yloxy)benzene-1-sulfonyl chloride (CAS 69129-62-0)
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- 3-(butan-2-yl)-1-[(6-methylpyridin-3-yl)methyl]piperazine (CAS 1423024-11-6)
- n-(Butan-2-yl)-2-methyl-1,2,3,4-tetrahydroquinoline-4-carboxamide (CAS 1134943-10-4)
- n-(Butan-2-yl)-2-methyl-decahydroquinoline-4-carboxamide, mixture of diastereomers (CAS 1240526-32-2)
- [4-(butan-2-yl)phenyl](thiophen-2-yl)methanamine (CAS 867329-90-6)
- (Butan-2-yl)[(2,3,4-trimethoxyphenyl)methyl]amine (CAS 893574-98-6)
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Recommended Standards
- Torasemide Impurity 47 (CAS 204499-30-9)
- N-(1-(4-Fluorophenyl)ethyl)thiophene-3-carboxamide (CAS 1032230-11-7)
- Sulfasalazine EP Impurity J (CAS 144-83-2)
- (3-Methyl-benzyl)-(2-trifluoromethylsulfanylethyl)-amine (CAS 1208079-13-3)
- Hexahydro-1-[2,4,8,10-tetrakis(1,1-dimethylethyl)dibenzo[d,f][1,3,2]dioxaphosphepin-6-yl]-1H-azepine (CAS 80399-60-6)
- 3-(4-Bromophenyl)-1h-pyrazole-4-carbaldehyde (CAS 350997-68-1)
- 4-[3-(Dibutylamino)propoxy]benzoic Acid-d6 Hydrochloride (CAS 1329808-49-2)
- 3-(5-Methylfuran-2-yl)-6-(piperazin-1-yl)pyridazine (CAS 1354916-71-4)
- (Z)-4-((4-(1,3-Dioxolan-2-yl)pyridin-2-yl)oxy)but-2-en-1-amine (CAS 118289-22-8)
- N-(3,5-dimethylphenyl)-2-((2,3,4,5,6-pentamethylbenzyl)thio)acetamide (CAS 329079-47-2)
- 1-(5-Bromopyrimidin-2-yl)cyclohexan-1-amine (CAS 1341745-05-8)
- tert-Butyl (3-aminopropyl)(tert-butyl)carbamate (CAS 1893475-27-8)
- Imidazo[1,2-a]quinoxalin-4-amine (CAS 38346-47-3)
- Atrial Natriuretic Polypeptide (4-28), human (CAS 95896-08-5)
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