N-(5-Amino-2-fluorophenyl)-2-[4-(tert-butyl)-phenoxy]propanamide CAS 1020053-98-8
| CAS No. | 1020053-98-8 |
| Molecular Formula | C19H23FN2O2 |
| Molecular Weight | 330.40 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including N-(5-Amino-2-fluorophenyl)-2-[4-(tert-butyl)-phenoxy]propanamide.
N-(5-Amino-2-fluorophenyl)-2-[4-(tert-butyl)-phenoxy]propanamide (CAS 1020053-98-8), molecular formula C19H23FN2O2 and molecular weight 330.40 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of N-(5-Amino-2-fluorophenyl)-2-[4-(tert-butyl)-phenoxy]propanamide (C19H23FN2O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), N-(5-Amino-2-fluorophenyl)-2-[4-(tert-butyl)-phenoxy]propanamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H23FN2O2 |
| Molecular Weight | 330.40 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related N Standards
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- N-(5-Amino-2-fluorophenyl)-4-(hexyloxy)benzamide (CAS 1020057-00-4)
- N-(5-Amino-2-fluorophenyl)-2-(hexyloxy)benzamide (CAS 1020057-19-5)
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- 4-((4-Amino-6-(2,5-dimethylbenzyl)-1,3,5-triazin-2-yl)amino)benzonitrile (CAS 205381-57-3)
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Recommended Standards
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- Urbacid (CAS 2445-07-0)
- Fluvoxamine Impurity 17 (CAS CATO-C4X-195117)
- 6-{1-[(prop-2-yn-1-yl)amino]ethyl}-3,4-dihydro-2h-1,4-benzoxazin-3-one (CAS 1038251-44-3)
- 2-(4-bromo-2-ethoxyphenyl)ethan-1-ol (CAS 943742-31-2)
- 4-(4-(1H-pyrrol-1-yl)phenyl)-1H-pyrazol-3-amine (CAS 1024019-01-9)
- 2-(3-bromo-5-iodophenyl)acetic acid (CAS 1261601-75-5)
- 5-(4-(2-(Methyl(pyridin-2-yl)amino)ethoxy)benzyl)-thiazolidine-2,4-dione hydrochloride (CAS 302543-62-0)
- 3,4-Dichloro-1H-pyrrolo[3,2-c]pyridine (CAS 117332-47-5)
- 6-(3,4-Dichlorophenyl)-2-hydroxy-4-[2-(trifluoromethyl)phenyl]pyridine-3-carbonitrile (CAS 478261-50-6)
- 2,5-Dimethoxybenzimidamide (CAS 343331-69-1)
- 1-(3,5-Di(thiophen-2-yl)-4,5-dihydro-1H-pyrazol-1-yl)-2-methylpropan-1-one (CAS 927556-27-2)
- Copper Peptide ·2 acetate salt (CAS 130120-57-9)
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