Rebastinib CAS 1020172-07-9
| CAS No. | 1020172-07-9 |
| Molecular Formula | C30H28FN7O3 |
| Molecular Weight | 553.59 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Rebastinib is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Rebastinib (CAS 1020172-07-9), a certified reference material (molecular formula C30H28FN7O3, MW 553.59 g/mol) for analytical method development and quality control.
Rebastinib (C30H28FN7O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Rebastinib meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C30H28FN7O3 |
| Molecular Weight | 553.59 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 20.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 7 |
Recommended Standards
- (S)-2-(((9H-FLuoren-9-yl)methoxy)carbonylamino)-6-(2-nitrophenylsulfonamido)hexanoic acid (CAS 359780-63-5)
- N-(2,5-Difluoro-4-((2-(1-methyl-1H-pyrazol-4-yl)pyridin-4-yl)oxy)phenyl)-N-phenylcyclopropane-1,1-dicarboxamide (CAS 1225278-16-9)
- Sulfasalazine Impurity 21 (CAS 2033064-44-5)
- Hydroxy O-Desmethyl Bosentan (CAS 253688-62-9)
- 1-Methyl-4-oxo-6-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxylic acid (CAS 1217071-29-8)
- 1-(2-Chloroethyl)pyridin-2(1h)-one (CAS 51323-39-8)
- 1-Chloro-4-(chloro(cyclohexyl)methyl)benzene (CAS 100614-59-3)
- 5-(1h-Pyrazol-5-yl)furan-2-carbaldehyde (CAS 1015939-90-8)
- N-methyl-4-(propan-2-yl)cyclohexan-1-amine hydrochloride (CAS 1803603-48-6)
- 5-Bromo-3-(p-tolyl)benzo[c]isoxazole (CAS 385386-97-0)
- (2-(Pyridin-3-yl)thiazol-4-yl)methanol (CAS 138745-99-0)
- 2-(Propylthio)ethan-1-ol (CAS 22812-90-4)
- 2-Nitro-5H-indolo[3,2-c]quinolin-6(11H)-one (CAS 1418414-05-7)
- Tirzepatide Impurity 14 (CAS CATO-C4X-324014)
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