2-((5-Amino-4-phenylthiazol-2-yl)thio)-N-(4-fluorobenzyl)acetamide CAS 1021030-54-5

Purity 97%+In StockPharmaceutical Standards
CAS No.1021030-54-5
Molecular FormulaC18H16FN3OS2
Molecular Weight373.47 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-((5-Amino-4-phenylthiazol-2-yl)thio)-N-(4-fluorobenzyl)acetamide CAS 1021030-54-5 chemical structure

Description

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

2-((5-Amino-4-phenylthiazol-2-yl)thio)-N-(4-fluorobenzyl)acetamide (CAS 1021030-54-5), molecular formula C18H16FN3OS2 and molecular weight 373.47 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 2-((5-Amino-4-phenylthiazol-2-yl)thio)-N-(4-fluorobenzyl)acetamide (C18H16FN3OS2) is characterized by a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

Physical & Chemical Properties

Molecular FormulaC18H16FN3OS2
Molecular Weight373.47 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)12.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1988
Halogen ContentF-containing
Nitrogen Atoms3
Sulfur Atoms2

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