3-Nitro-5-(trifluoromethyl)-1H-pyrazole CAS 1021430-20-5

Purity 97%+In StockPharmaceutical Standards
CAS No.1021430-20-5
Molecular FormulaC4H2F3N3O2
Molecular Weight181.07 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

3-Nitro-5-(trifluoromethyl)-1H-pyrazole CAS 1021430-20-5 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-Nitro-5-(trifluoromethyl)-1H-pyrazole.

3-Nitro-5-(trifluoromethyl)-1H-pyrazole (CAS 1021430-20-5) is a high-purity analytical reference standard with the molecular formula C4H2F3N3O2 and a molecular weight of 181.07 g/mol.

3-Nitro-5-(trifluoromethyl)-1H-pyrazole (C4H2F3N3O2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 3-Nitro-5-(trifluoromethyl)-1H-pyrazole under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC4H2F3N3O2
Molecular Weight181.07 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1988
Halogen ContentF-containing
Nitrogen Atoms3

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