1-(2-Phenoxypyridine-3-carbonyl)-4-phenylpiperazine CAS 1022582-89-3
| CAS No. | 1022582-89-3 |
| Molecular Formula | C22H21N3O2 |
| Molecular Weight | 359.42 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-(2-Phenoxypyridine-3-carbonyl)-4-phenylpiperazine (CAS 1022582-89-3), molecular formula C22H21N3O2 and molecular weight 359.42 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-(2-Phenoxypyridine-3-carbonyl)-4-phenylpiperazine (C22H21N3O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H21N3O2 |
| Molecular Weight | 359.42 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Nitrogen Atoms | 3 |
Related Phenoxypyridine Standards
- 2-Phenoxypyridine-4-boronic acid pinacol ester (CAS 2096331-18-7)
- 2-Phenoxypyridine-5-boronic acid pinacol ester, 97% (CAS 330792-76-2)
- 6-Phenoxypyridine-3-sulfonyl chloride (CAS 368869-91-4)
- 3-phenoxypyridine-2-carboxylic acid (CAS 103877-89-0)
- 2-Phenoxypyridine-4-carboxylic acid (CAS 51362-08-4)
- 3-phenoxypyridine-4-carboxylic acid (CAS 54629-99-1)
- 4-Phenoxypyridine-3-carboxylic acid (CAS 54629-95-7)
- 5-Phenoxypyridine-3-carboxylic acid (CAS 668969-15-1)
Recommended Standards
- 1-(Benzo[d][1,3]dioxol-5-yl)-6-methyl-2-(p-tolyl)-1,5,6,7-tetrahydro-4H-indol-4-one (CAS 1022133-72-7)
- 5-Amino-7-methoxy-8-(3-morpholinopropoxy)-2,3-dihydroimidazo[1,2-c]quinazoline (CAS 1032570-74-3)
- Penthiopyrad (CAS 183675-82-3)
- (Tert-butoxycarbonyl)-L-isoleucyl-L-glutamine (CAS 104903-59-5)
- Iodomethyl methyl ether (CAS 13057-19-7)
- 1-(2,4-Dimethoxy-3-methylphenyl)propan-1-one (CAS 77942-13-3)
- 3-Fluoro-5-isopropoxyphenylboronic acid (CAS 1195945-65-3)
- 1-Hydroxy-3-methyl-2-phenyl-1H-benzo[d]imidazol-3-ium tetrafluoroborate (CAS 2443473-68-3)
- Bisphenol A,formaldehyde resin (CAS 25085-75-0)
- 1-(Tert-butyl) 2-methyl (S)-4,4-difluoropiperidine-1,2-dicarboxylate (CAS 1352342-07-4)
- 2-(2,5-Dimethoxyphenyl)quinoline-4-carbonyl chloride (CAS 1160264-87-8)
- N-(4-Amino-2-methylphenyl)-2-(2-isopropyl-5-methylphenoxy)acetamide (CAS 1020057-26-4)
- 3-(Benzyloxy)-2-methylpropan-1-ol (CAS 64839-09-4)
- Semaglutide Impurity 167 (CAS CATO-C4X-2226167)
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