tert-butyl (2S)-2-(2-chloroacetyl)pyrrolidine-1-carboxylate CAS 102284-41-3
| CAS No. | 102284-41-3 |
| Molecular Formula | C11H18ClNO3 |
| Molecular Weight | 247.72 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of tert-butyl (2S)-2-(2-chloroacetyl)pyrrolidine-1-carboxylate (C11H18ClNO3) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
tert-butyl (2S)-2-(2-chloroacetyl)pyrrolidine-1-carboxylate (CAS 102284-41-3) is a high-purity analytical reference standard with the molecular formula C11H18ClNO3 and a molecular weight of 247.72 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H18ClNO3 |
| Molecular Weight | 247.72 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
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- 4-Chloro-6-methyl-N-(4-methylbenzyl)pyrimidin-2(1h)-imine (CAS 1031046-21-5)
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- 4,6-Dichloro-2-methylpyrimidine-5-carbaldehyde (CAS 14160-91-9)
- Methyl 2-((3-oxo-1-phenyl-2,3-dihydro-1H-inden-4-yl)thio)acetate (CAS 337921-72-9)
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- 9-Hydroxybenz[a]anthracene (CAS 34570-62-2)
- Semaglutide Impurity 146 (CAS 2645421-68-5)
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