1-[(4-Bromo-3-fluorophenyl)carbonyl]pyrrolidine CAS 1022931-81-2
| CAS No. | 1022931-81-2 |
| Molecular Formula | C11H11BrFNO |
| Molecular Weight | 272.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies 1-[(4-Bromo-3-fluorophenyl)carbonyl]pyrrolidine (CAS 1022931-81-2), a certified reference material (molecular formula C11H11BrFNO, MW 272.11 g/mol) for analytical method development and quality control.
The molecular framework of 1-[(4-Bromo-3-fluorophenyl)carbonyl]pyrrolidine (C11H11BrFNO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C11H11BrFNO |
| Molecular Weight | 272.11 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
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Recommended Standards
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- 2-(3-(Difluoromethyl)-5-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 627526-04-9)
- (S)-4-(1-Aminoethyl)-2-methoxybenzoic acid hydrochloride (CAS 2216747-15-6)
- 2-Methylbutane-1,2,3,4-tetraol (CAS 42933-13-1)
- N-(3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)cyclopropanecarboxamide (CAS 1031747-40-6)
- 2-(2H-1,3-Benzodioxol-5-yl)-3-bromoimidazo[1,2-a]pyridine (CAS 904813-89-4)
- (R)-4-Cyano-N-(1-(1-ethyl-6-(trifluoromethyl)-1H-benzo[d]imidazol-2-yl)ethyl)benzenesulfonamide (CAS 1025506-51-7)
- 3-Cyclopropyl-6-methyl-1-phenyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid (CAS 1018127-41-7)
- Tirzepatide Impurity 46 (CAS CATO-C4X-324046)
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