1,1-Diphenyl-3-(p-tolyl)isoquinolin-4(1H)-one CAS 102301-79-1

Purity 97%+In StockPharmaceutical Standards
CAS No.102301-79-1
Molecular FormulaC28H21NO
Molecular Weight387.47 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1,1-Diphenyl-3-(p-tolyl)isoquinolin-4(1H)-one CAS 102301-79-1 chemical structure

Description

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

1,1-Diphenyl-3-(p-tolyl)isoquinolin-4(1H)-one (CAS 102301-79-1), molecular formula C28H21NO and molecular weight 387.47 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 1,1-Diphenyl-3-(p-tolyl)isoquinolin-4(1H)-one (C28H21NO) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

Physical & Chemical Properties

Molecular FormulaC28H21NO
Molecular Weight387.47 g/mol
AppearancePale yellow to yellow crystalline powder
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)19.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1986
Nitrogen Atoms1

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