3-Acetyl-6-fluoroquinolin-4(1H)-one CAS 1023293-18-6
| CAS No. | 1023293-18-6 |
| Molecular Formula | C11H8FNO2 |
| Molecular Weight | 205.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
3-Acetyl-6-fluoroquinolin-4(1H)-one (CAS 1023293-18-6) is a high-purity analytical reference standard with the molecular formula C11H8FNO2 and a molecular weight of 205.19 g/mol.
The molecular framework of 3-Acetyl-6-fluoroquinolin-4(1H)-one (C11H8FNO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H8FNO2 |
| Molecular Weight | 205.19 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Acetyl Standards
- 2-(7-Fluoroquinolin-6-yl)acetic acid (CAS 1022091-54-8)
- 3-Acetyl-7-fluoroquinolin-4(1H)-one (CAS 1023293-76-6)
- 3-Acetyl-8-fluoroquinolin-4(1H)-one (CAS 1023294-06-5)
- N-(3-Fluoroquinolin-8-yl)acetamide (CAS 155014-06-5)
- 2-((5-Fluoroquinolin-8-yl)oxy)acetonitrile (CAS 88757-38-4)
- 1-Ethyl-6-fluoroquinolin-4(1H)-one (CAS 1210718-46-9)
- 1-Ethyl-8-fluoroquinolin-4(1H)-one (CAS 1211795-81-1)
- 2-(6-Fluoroquinolin-2-yl)ethanol (CAS 1433203-67-8)
Recommended Standards
- 102186-93-6 N-(2-Fluorophenyl)-1H-imidazole-5-carboxamide MFCD21648536 (CAS 102186-93-6)
- 1-(3-Fluoro-4-(1h-1,2,4-triazol-1-yl)phenyl)ethan-1-one (CAS 1019570-54-7)
- 1-(2-Fluoro-4-methylphenyl)-1H-pyrrole-2,5-dione (CAS 1030420-86-0)
- 1-(2-Fluoro-6-(1h-1,2,4-triazol-1-yl)phenyl)ethan-1-one (CAS 1019528-36-9)
- Biotin-XX, SSE, 90% (CAS 194041-66-2)
- 3-Chloro-2-[(1E)-{2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]hydrazin-1-ylidene}(phenyl)methyl]-5-(trifluoromethyl)pyridine (CAS 339106-63-7)
- Methyl-(6-piperidin-4-ylmethyl-pyrimidin-4-yl)-amine dihydrochloride (CAS 1361113-43-0)
- Methyl 2-phenyl-2-(piperazin-1-yl)acetate (CAS 864932-46-7)
- PCB No. 166 (CAS 41411-63-6)
- 6-Imino-6H-purin-8-amine (CAS 865149-66-2)
- 3,4-Diisobutoxycyclobut-3-ene-1,2-dione (CAS 61699-64-7)
- 2-Decylmalonic acid (CAS 4372-29-6)
- Methyl 5-(2-(aminomethyl)phenyl)-1H-pyrazole-3-carboxylate hydrochloride (CAS 1609082-47-4)
- Tirzepatide Impurity 24 X TFA Salt (CAS CATO-C4X-324024)
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