1-(4-((6,7-Dimethoxy-3,4-dihydroisoquinolin-1-yl)methyl)phenyl)-3-(3-fluoro-4-methylphenyl)urea CAS 1023435-48-4
| CAS No. | 1023435-48-4 |
| Molecular Formula | C26H26FN3O3 |
| Molecular Weight | 447.50 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1-(4-((6,7-Dimethoxy-3,4-dihydroisoquinolin-1-yl)methyl)phenyl)-3-(3-fluoro-4-methylphenyl)urea is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
1-(4-((6,7-Dimethoxy-3,4-dihydroisoquinolin-1-yl)methyl)phenyl)-3-(3-fluoro-4-methylphenyl)urea (CAS 1023435-48-4), molecular formula C26H26FN3O3 and molecular weight 447.50 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 1-(4-((6,7-Dimethoxy-3,4-dihydroisoquinolin-1-yl)methyl)phenyl)-3-(3-fluoro-4-methylphenyl)urea is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 447.50 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C26H26FN3O3 |
| Molecular Weight | 447.50 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Dimethoxy Standards
- 1-(4-((6,7-Dimethoxy-3,4-dihydroisoquinolin-1-yl)methyl)phenyl)-3-(5-fluoro-2-methylphenyl)urea (CAS 1022256-59-2)
- 3-(Dimethoxy)-5-(tributylstannyl)pyridine (CAS 1264193-67-0)
- 2,5-Dimethoxy-3-methyl-6-((E)-nonadec-14-enyl)[1,4]benzoquinone (CAS 4146-42-3)
- 6-{[2-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-2-yl)-2-oxoethyl]sulfanyl}-[2,3'-bipyridine]-5-carbonitrile (CAS 496804-90-1)
- 4,4'-Dimethoxy-2,2'5,5'-tetraacetoxybiphenyl (CAS 7461-72-5)
- 1-(4-((6,7-Dimethoxy-3,4-dihydroisoquinolin-1-yl)methyl)phenyl)-3-(2-methoxyphenyl)urea (CAS 1022326-43-7)
- 3-(4,8-Dimethoxy-9H-pyrido[3,4-b]indol-1-yl)-1-(9H-pyrido[3,4-b]indol-1-yl)propan-1-one (CAS 82652-20-8)
- 2,5-Dimethoxy-N-(1-(3-(pyridin-3-yl)-1,2,4-oxadiazol-5-yl)cyclohexyl)benzenesulfonamide (CAS 1396799-72-6)
Recommended Standards
- (2R,4R)-1-Benzyl 2-ethyl 4-(tosyloxy)pyrrolidine-1,2-dicarboxylate (CAS 130830-60-3)
- Siponimod impurity 21 (CAS CATO-C4X-247221)
- Pitavastatin 3-Oxo Ethyl Ester (CAS 148901-69-3)
- Oxaline (CAS 55623-37-5)
- 5-Cyclopropoxy-4-methoxy-N-methylpyridin-2-amine (CAS 1243381-57-8)
- 1-(6-(Benzyloxy)-4-methylpyridin-3-yl)propan-1-one (CAS 1355179-34-8)
- 4-Chloro-7-methoxy-6-methylquinoline-3-carbonitrile (CAS 1259017-80-5)
- 2-Benzyl-1,3-diazaspiro[4.4]non-2-en-4-one (CAS 737742-80-2)
- (S)-1-Chloropropan-2-ol (CAS 37493-16-6)
- 2-({[2-nitro-5-(trifluoromethyl)phenyl]amino}methylidene)-2,3-dihydro-1H-indene-1,3-dione (CAS 1023502-21-7)
- Methyl 2-(2-(3,4-dimethoxyphenyl)thiazol-4-yl)acetate (CAS 1081137-63-4)
- Tert-butyl 3-((4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)methyl)piperidine-1-carboxylate (CAS 2365173-87-9)
- 1-(Benzyloxy)-4-chloro-2,3-difluorobenzene (CAS 1881295-93-7)
- Fibrinogen-Binding Peptide (CAS 137235-80-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com