6-Methyl-N-(4-(trifluoromethoxy)phenyl)-3,4-dihydroquinoline-1(2H)-carbothioamide CAS 1024052-82-1

Purity 97%+In StockPharmaceutical Standards
CAS No.1024052-82-1
Molecular FormulaC18H17F3N2OS
Molecular Weight366.40 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

6-Methyl-N-(4-(trifluoromethoxy)phenyl)-3,4-dihydroquinoline-1(2H)-carbothioamide CAS 1024052-82-1 chemical structure

Description

The molecular framework of 6-Methyl-N-(4-(trifluoromethoxy)phenyl)-3,4-dihydroquinoline-1(2H)-carbothioamide (C18H17F3N2OS) is characterized by a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

CATO supplies 6-Methyl-N-(4-(trifluoromethoxy)phenyl)-3,4-dihydroquinoline-1(2H)-carbothioamide (CAS 1024052-82-1), a certified reference material (molecular formula C18H17F3N2OS, MW 366.40 g/mol) for analytical method development and quality control.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 6-Methyl-N-(4-(trifluoromethoxy)phenyl)-3,4-dihydroquinoline-1(2H)-carbothioamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC18H17F3N2OS
Molecular Weight366.40 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)10.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1988
Halogen ContentF-containing
Nitrogen Atoms2
Sulfur Atoms1

Recommended Standards

Why CATO?