4,4-Dimethyl-2,6-dioxo-N-[3-(trifluoromethyl)phenyl]cyclohexane-1-carbothioamide CAS 1024251-56-6
| CAS No. | 1024251-56-6 |
| Molecular Formula | C16H16F3NO2S |
| Molecular Weight | 343.36 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4,4-Dimethyl-2,6-dioxo-N-[3-(trifluoromethyl)phenyl]cyclohexane-1-carbothioamide (CAS 1024251-56-6), molecular formula C16H16F3NO2S and molecular weight 343.36 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4,4-Dimethyl-2,6-dioxo-N-[3-(trifluoromethyl)phenyl]cyclohexane-1-carbothioamide (C16H16F3NO2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 4,4-Dimethyl-2,6-dioxo-N-[3-(trifluoromethyl)phenyl]cyclohexane-1-carbothioamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H16F3NO2S |
| Molecular Weight | 343.36 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
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Recommended Standards
- N-(5-(Thiophen-2-ylmethyl)-1,3,4-oxadiazol-2-yl)-2,3-dihydrobenzo[b][1,4]dioxine-6-carboxamide (CAS 1021051-91-1)
- N-(3-Nitro-2-pyridinesulfenyl)-L-aspartic acid β-t-butyl ester (CAS 108312-24-9)
- Sunitinib Impurity 21 (CAS CATO-C4X-133321)
- (2S,4R)-2-[(Dimethylamino)carbonyl]-4-hydroxy-1-pyrrolidinecarboxylic Acid-d6 4-Nitrobenzyl Ester (CAS 1246814-87-8)
- 1,1′-Di-2-naphthol bis(trifluoromethanesulfonate) (CAS 128575-34-8)
- 2-(Bromomethyl)-6-(difluoromethyl)-3-hydroxy-4-methoxypyridine (CAS 1805250-77-4)
- n-Methyl-1-(4-(pentafluoro-lambda6-sulfanyl)phenyl)methanamine (CAS 1287217-84-8)
- 5-((3-Chlorobenzyl)thio)-3-(cyclohexylmethyl)-8,9-dimethoxyimidazo[1,2-c]quinazolin-2(3H)-one (CAS 1024017-13-7)
- 1-Methyl-6-oxa-3-thiabicyclo[3.1.0]hexane 3,3-dioxide (CAS 18502-58-4)
- 7-Bromo-1-fluoronaphthalene (CAS 319-04-0)
- Pentamethylene Diisocyanate (CAS 4538-42-5)
- Potassium 2-amino-1,3-benzothiazole-6-carboxylate (CAS 1017488-71-9)
- Ethyl 2,4-dichlorothiazole-5-carboxylate (CAS 125759-82-2)
- FMRF-Like Neuropeptide (CAS 121801-61-4)
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