3-(2-Chlorophenyl)-N-(2-fluoro-5-(trifluoromethyl)phenyl)-5-methylisoxazole-4-carboxamide CAS 1024259-34-4
| CAS No. | 1024259-34-4 |
| Molecular Formula | C18H11ClF4N2O2 |
| Molecular Weight | 398.74 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-(2-Chlorophenyl)-N-(2-fluoro-5-(trifluoromethyl)phenyl)-5-methylisoxazole-4-carboxamide.
CATO supplies 3-(2-Chlorophenyl)-N-(2-fluoro-5-(trifluoromethyl)phenyl)-5-methylisoxazole-4-carboxamide (CAS 1024259-34-4), a certified reference material (molecular formula C18H11ClF4N2O2, MW 398.74 g/mol) for analytical method development and quality control.
The molecular framework of 3-(2-Chlorophenyl)-N-(2-fluoro-5-(trifluoromethyl)phenyl)-5-methylisoxazole-4-carboxamide (C18H11ClF4N2O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 3-(2-Chlorophenyl)-N-(2-fluoro-5-(trifluoromethyl)phenyl)-5-methylisoxazole-4-carboxamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H11ClF4N2O2 |
| Molecular Weight | 398.74 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
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- 2-(Propylsulfanyl)-3H-indol-3-one N-(2,4,6-trichlorophenyl)hydrazone (CAS 478042-25-0)
- (4-(Tert-butoxy)phenyl)diphenylsulfonium chloride (CAS 199733-54-5)
- Granisetron Impurity 27 (CAS 10604-20-3)
- 5-Chloro-2,4-difluorobenzyl alcohol (CAS 915409-63-1)
- 2-Amino-5-pyrimidinol (CAS 143489-45-6)
- 1-(3-Bromophenyl)-3-phenylurea (CAS 2989-97-1)
- 5-Bromo-2,3-dihydro-1-benzofuran-2-one (CAS 166386-69-2)
- Tert-butyl 4-amino-3-methylbenzoate (CAS 934481-43-3)
- 4-(3-Chloro-4-fluoro-phenyl)-5-(2,4-dichloro-phenyl)-4H-[1,2,4]triazole-3-thiol (CAS 380346-00-9)
- 2-cyano-3-(1H-pyrrolo[2,3-b]pyridin-3-ly)-2-Propenamide (CAS 157561-90-5)
- RGD-targeted Proapoptotic Peptide trifluoroacetate salt (CAS 2243207-09-0)
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