8-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)-2-methylquinoline CAS 1024367-69-8
| CAS No. | 1024367-69-8 |
| Molecular Formula | C16H10ClF3N2O |
| Molecular Weight | 338.71 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
8-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)-2-methylquinoline (CAS 1024367-69-8) is a high-purity analytical reference standard with the molecular formula C16H10ClF3N2O and a molecular weight of 338.71 g/mol.
8-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)-2-methylquinoline (C16H10ClF3N2O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H10ClF3N2O |
| Molecular Weight | 338.71 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-1-phenyl-1H-pyrazol-5-amine (CAS 1823183-91-0)
- 1-(1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-1H-indol-3-yl)ethan-1-one (CAS 339099-11-5)
- 2-(2-Chloro-4-(1H-pyrrol-1-yl)phenoxy)-5-(trifluoromethyl)pyridine (CAS 338397-70-9)
- 2-(2-Chloro-4-(trifluoromethyl)phenyl)-4-methylphthalazin-1(2H)-one (CAS 551921-15-4)
- 2-(4-Chloro-2-methylphenoxy)-3-(trifluoromethyl)quinoxaline (CAS 338773-64-1)
- 3-Chloro-2-[3-(1H-pyrrol-1-yl)phenoxy]-5-(trifluoromethyl)pyridine (CAS 338786-02-0)
- 3-Chloro-2-[phenyl(1H-1,2,4-triazol-3-yl)methyl]-5-(trifluoromethyl)pyridine (CAS 338407-00-4)
- 4-(4-Chloro-2-methylphenoxy)-2-(trifluoromethyl)quinazoline (CAS 303148-90-5)
Recommended Standards
- Afatinib Impurity 65 (CAS CATO-C4X-100665)
- 4'-Fluoro-5-(trifluoromethyl)biphenyl-2-sulfonyl chloride (CAS 1214360-14-1)
- Bis(N,N-dimethyl-β-alaninato)palladium(II) (CAS 934215-85-7)
- 26RU378B9V 1258453-75-6 ABX-464 UNII-26RU378B9V SPL-464 2-Quinolinamine, 8-chloro-N-(4-(trifluoromethoxy)phenyl)- 8-Chloro-N-(4-(trifluoromethoxy)phenyl)quinolin-2-amine ABX464 (CAS 1258453-75-6)
- 2-(3-Ethylpentan-3-yl)pyrazine (CAS 106073-56-7)
- 4-Methoxycarbonylphenylboronic acid pinacol ester (CAS 171364-80-0)
- 5-methoxybenzothiophene-2-sulfonyl chloride (CAS 96803-99-5)
- Pyridoxine Impurity 45 HCl (CAS 19203-53-3(Free base))
- 3,5-Dichloro-1,2,4-triazine (CAS 59631-75-3)
- 1,4-Diphenyl-3,4-dihydroisoquinoline (CAS 77988-87-5)
- 3-[(3-aminophenyl)ethynyl]benzoic acid (CAS 930395-90-7)
- 1-Bromo-4-fluoro-2-((2,2,2-trifluoroethoxy)methyl)benzene (CAS 1704065-28-0)
- Coenzyme A Disulfide (CAS 31664-36-5)
- [His]1-Acetylated Semaglutide (CAS CATO-C4X-2226219)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com