6-Chloro-2,4-bis(4-morpholinyl)pyrimidine CAS 10244-24-3

Purity 97%+In StockPharmaceutical Standards
CAS No.10244-24-3
Molecular FormulaC12H17ClN4O2
Molecular Weight284.74 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

6-Chloro-2,4-bis(4-morpholinyl)pyrimidine CAS 10244-24-3 chemical structure

Description

The occurrence of 6-Chloro-2,4-bis(4-morpholinyl)pyrimidine is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies 6-Chloro-2,4-bis(4-morpholinyl)pyrimidine (CAS 10244-24-3), a certified reference material (molecular formula C12H17ClN4O2, MW 284.74 g/mol) for analytical method development and quality control.

The molecular framework of 6-Chloro-2,4-bis(4-morpholinyl)pyrimidine (C12H17ClN4O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 6-Chloro-2,4-bis(4-morpholinyl)pyrimidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC12H17ClN4O2
Molecular Weight284.74 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1959
Halogen ContentCl-containing
Nitrogen Atoms4

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