2-(((4-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)thio)phenyl)amino)methylene)malononitrile CAS 1024414-83-2
| CAS No. | 1024414-83-2 |
| Molecular Formula | C16H8ClF3N4S |
| Molecular Weight | 380.77 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 2-(((4-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)thio)phenyl)amino)methylene)malononitrile (CAS 1024414-83-2), a certified reference material (molecular formula C16H8ClF3N4S, MW 380.77 g/mol) for analytical method development and quality control.
The molecular framework of 2-(((4-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)thio)phenyl)amino)methylene)malononitrile (C16H8ClF3N4S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO manufactures 2-(((4-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)thio)phenyl)amino)methylene)malononitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H8ClF3N4S |
| Molecular Weight | 380.77 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 4-{[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}-N-ethylbenzenesulfonamide (CAS 1427460-37-4)
- 6-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-3-(thiophen-2-yl)pyrazolo[1,5-a]pyrimidine (CAS 338953-47-2)
- 1-Chloro-7-methoxy-4-nitro-9-phenoxyacridine (CAS 134039-84-2)
- 2-Chloro-1,5-dihydroxy-6-(4-methoxyphenyl)anthracene-9,10-dione (CAS 92753-68-9)
- 7-Chloro-4-nitro-1-(p-tolyloxy)acridin-9(10H)-one (CAS 61290-20-8)
- 1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(pyridin-2-ylmethyl)-1H-pyrrole-2-carboxamide (CAS 338397-53-8)
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Recommended Standards
- AT 265 (CAS 66522-52-9)
- N-(4-chlorophenyl)-5-methyl-1-(3-(trifluoromethyl)phenyl)-1H-1,2,4-triazole-3-carboxamide (CAS 321431-38-3)
- (E)-N'-({1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-1H-pyrrol-2-yl}sulfonyl)-N,N-dimethylmethanimidamide (CAS 338406-54-5)
- 5-(4-Chlorophenyl)-1-(3-(trifluoromethyl)phenyl)-1H-pyrazole-3-carbohydrazide (CAS 955976-46-2)
- 3-(Methylamino)-2,3-dihydro-1H-indene-5-carboxylic acid (CAS 1780458-94-7)
- 14390-75-1 Tellurium, isotope of mass 128 Tellurium-128 128Te (CAS 14390-75-1)
- N,1-dimethyl-N-[2-(methylamino)ethyl]piperidin-4-amine (CAS 1020945-27-0)
- 2,4,5-Tribromo-1-methylimidazole (CAS 1003-91-4)
- 2-Bromo-2-methyl-N-(thiazol-2-yl)propanamide (CAS 301165-22-0)
- 2-((2-(3-Methylthiomorpholino)-2-oxoethyl)thio)acetic acid (CAS 1565537-64-5)
- 4-Bromo-2-(((2,4-difluorophenyl)amino)methyl)-6-methoxyphenol (CAS 329778-59-8)
- 2’-Deoxy-2’-fluoro-b-D-arabinocytidine (CAS 56632-83-8)
- (R)-methyl piperidine-3-carboxylate (CAS 164323-85-7)
- Semaglutide Impurity 147 (CAS CATO-C4X-2226147)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com