N'-((1H-Indol-3-yl)methylene)-2-hydroxybenzohydrazide CAS 10245-40-6
| CAS No. | 10245-40-6 |
| Molecular Formula | C16H13N3O2 |
| Molecular Weight | 279.29 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 279.29 g/mol gives N'-((1H-Indol-3-yl)methylene)-2-hydroxybenzohydrazide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
N'-((1H-Indol-3-yl)methylene)-2-hydroxybenzohydrazide (CAS 10245-40-6), molecular formula C16H13N3O2 and molecular weight 279.29 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, N'-((1H-Indol-3-yl)methylene)-2-hydroxybenzohydrazide (C16H13N3O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 279.29 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), N'-((1H-Indol-3-yl)methylene)-2-hydroxybenzohydrazide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H13N3O2 |
| Molecular Weight | 279.29 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1959 |
| Nitrogen Atoms | 3 |
Recommended Standards
- (E)-2-(((4,6-dimethylpyrimidin-2-yl)imino)methyl)-3-hydroxy-1H-inden-1-one (CAS 1024146-89-1)
- 1-[(naphthalen-1-yl)methyl]-6-oxo-1,6-dihydropyridine-3-carboxylic acid (CAS 1036565-76-0)
- Methyl (6,7-dimethoxy-2-oxo-1,2,3,4-tetrahydroquinolin-4-yl)acetate (CAS 1020242-41-4)
- 1-(Naphthalen-1-ylmethyl)-2-oxo-1,2-dihydropyridine-3-carboxylic acid (CAS 1037083-71-8)
- (1R,3R,4R,7S)-3-(4-Amino-5-methyl-2-oxopyrimidin-1(2H)-yl)-1-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-2,5-dioxabicyclo[2.2.1]heptan-7-yl (2-cyanoethyl) diisopropylphosphoramidite (CAS 1184723-53-2)
- Methyl 4-(Bromomethyl)-2,5-difluorobenzoate (CAS 1355488-72-0)
- 2-{[(4-chlorophenyl)methyl]sulfanyl}-4-(cyclohexylsulfanyl)-5,6,7,8-tetrahydroquinazoline (CAS 339019-13-5)
- 1-Chloro-3-isopropoxypropan-2-one (CAS 63611-47-2)
- (2,3-Difluoro-4-propoxyphenyl)boronic acid (CAS 212837-49-5)
- 2-(pentyloxy)acetic acid (CAS 5416-03-5)
- Ethyl 5-bromo-3-phenyl-1H-indole-2-carboxylate (CAS 59394-42-2)
- 2-(Quinolin-4-yl)acetaldehyde (CAS 545423-96-9)
- n,n'-(Benzo[d][1,3]dioxol-5-ylmethylene)diacetamide (CAS 14683-73-9)
- Liraglutide Impurity 22 (CAS 536721-25-2)
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