5-(((2-Chlorothiazol-4-yl)methyl)thio)-3-isopropyl-8,9-dimethoxyimidazo[1,2-c]quinazolin-2(3H)-one CAS 1024618-15-2
| CAS No. | 1024618-15-2 |
| Molecular Formula | C19H19ClN4O3S2 |
| Molecular Weight | 450.96 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies 5-(((2-Chlorothiazol-4-yl)methyl)thio)-3-isopropyl-8,9-dimethoxyimidazo[1,2-c]quinazolin-2(3H)-one (CAS 1024618-15-2), a certified reference material (molecular formula C19H19ClN4O3S2, MW 450.96 g/mol) for analytical method development and quality control.
The molecular framework of 5-(((2-Chlorothiazol-4-yl)methyl)thio)-3-isopropyl-8,9-dimethoxyimidazo[1,2-c]quinazolin-2(3H)-one (C19H19ClN4O3S2) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H19ClN4O3S2 |
| Molecular Weight | 450.96 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 2 |
Related Chlorothiazol Standards
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Recommended Standards
- Halcinonide Impurity 17 (CAS CATO-C4X-279517)
- N-(4-Chlorobenzyl)-3-((4-methoxy-N-methylphenyl)sulfonamido)thiophene-2-carboxamide (CAS 1115871-65-2)
- Halcinonide Impurity 13 (CAS CATO-C4X-279513)
- N-(3-Chlorobenzyl)-3-((4-methoxy-N-methylphenyl)sulfonamido)thiophene-2-carboxamide (CAS 1115933-60-2)
- 3-Bromo-2-fluoro-6-(trifluoromethyl)pyridine (CAS 1159512-36-3)
- Octadecylphosphophosphoniumcholine (CAS 156825-89-7)
- 3-Amino-4-(dimethylamino)-N-methylbenzamide hydrochloride (CAS 1324077-91-9)
- Trisodium Glycyrrhizinate (CAS 71277-78-6)
- 7-Bromoquinolin-4-amine (CAS 65340-74-1)
- 4-Cyclopropoxy-5-(dimethylamino)nicotinic acid (CAS 1243345-98-3)
- 2-Chloro-4-methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline (CAS 2121513-87-7)
- Cholesterol Isopropyl Carbonate (CAS 78916-25-3)
- 1-Acetyl-4-methoxyimidazolidin-2-one (CAS 320778-06-1)
- Semaglutide impurity 255 (CAS CATO-C4X-2226255)
Why CATO?
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