(2E)-3-{4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}-2-{[3-(trifluoromethyl)phenyl]methanesulfonyl}prop-2-enenitrile CAS 1024754-35-5
| CAS No. | 1024754-35-5 |
| Molecular Formula | C21H17ClF6N4O2S |
| Molecular Weight | 538.89 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures (2E)-3-{4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}-2-{[3-(trifluoromethyl)phenyl]methanesulfonyl}prop-2-enenitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
(2E)-3-{4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}-2-{[3-(trifluoromethyl)phenyl]methanesulfonyl}prop-2-enenitrile (CAS 1024754-35-5) is a high-purity analytical reference standard with the molecular formula C21H17ClF6N4O2S and a molecular weight of 538.89 g/mol.
The molecular framework of (2E)-3-{4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}-2-{[3-(trifluoromethyl)phenyl]methanesulfonyl}prop-2-enenitrile (C21H17ClF6N4O2S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H17ClF6N4O2S |
| Molecular Weight | 538.89 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related E Standards
- N-(2-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)amino)ethyl)-4-fluoro-N-((3-(hydrazinecarbonyl)-4,5-dihydroisoxazol-5-yl)methyl)benzenesulfonamide (CAS 338961-92-5)
- 3-((4-Chloro-2-phosphonophenyl)diazenyl)-4,5-dihydroxynaphthalene-2,7-disulfonic acid (CAS 1938-82-5)
- (S)-2-(3-Chloro-4-fluorobenzyl)-8-ethyl-10-hydroxy-6-methyl-4-(5-methyl-1,1-dioxido-1,2,5-thiadiazolidin-2-yl)-7,8-dihydropyrazino[1',2':1,5]pyrrolo[2,3-d]pyridazine-1,9(2H,6H)-dione (CAS 1334669-63-4)
- 4-Chloro-N-(2-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)amino)ethyl)-N-(4-chlorobenzyl)benzenesulfonamide (CAS 338406-40-9)
- 6-Chloro-2-iodo-9-(2’,3’,5’-tri-O-acetyl-β-D-ribofuranosyl)purine (CAS 5987-76-8)
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- 4-Chloro-N-[1-(2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}ethyl)-2,5-dioxo-1,2,5,6,7,8-hexahydroquinolin-3-yl]benzamide (CAS 477864-88-3)
- 4-Chloro-N-(4-chlorophenyl)-N-[(2,3-diphenyl-1,2-oxazolidin-5-yl)methyl]benzene-1-sulfonamide (CAS 306978-08-5)
Recommended Standards
- 2,4,5-Trichloro-N-(1-(4-methoxybenzyl)-2,5,6-trimethyl-1H-benzo[d]imidazol-4-yl)benzenesulfonamide (CAS 338964-25-3)
- 9-PAHSA (CAS 1481636-31-0)
- 6(R)-[2-(8(S)-(2,2-Dimethyl-d6-butyryl)oxy]-2(S),6(R)-dimethyl-1,2,6,7,8,8a(R)-hexahydro-1(S)-naphthyl]ethyl-4(R)-(t-butyl-dimethylsilyl)oxy-3,4,5,6-tetrahydro-2H-pyran-2-one (CAS 1335460-29-1)
- 5-PAHSA (CAS 1481636-41-2)
- Ethyl ((4-(thiophen-2-yl)tetrahydro-2H-pyran-4-yl)methyl)carbamate (CAS 1206994-09-3)
- ethyl 3-azido-2-hydroxypropanoate (CAS 144888-69-7)
- 5-Chloro-2-nitrobenzenethiol (CAS 14371-79-0)
- 4-[(1,3,5-Trimethyl-1H-pyrazol-4-yl)methyl]phenyl benzoate (CAS 318284-36-5)
- 3-Hydroxy-2-methoxybenzaldehyde (CAS 66495-88-3)
- N-[S-(2-Pyridylthioethyl)-t-Boc-aminooxyacetamide (CAS 887407-46-7)
- Tenuazonic Acid Copper Salt (CAS 12427-40-6)
- (2-Chloro-4-(diisopropylcarbamoyl)phenyl)boronic acid (CAS 2096331-79-0)
- 2-(Methylthio)pyridin-3-amine (CAS 38240-22-1)
- Endo-[Glu]31-Liraglutide (CAS CATO-C4X-199234)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com