(Z)-2-(2,2-dimethylpropanoyl)-3-[4-(2-fluorophenyl)piperazino]-2-propenenitrile CAS 1025124-66-6
| CAS No. | 1025124-66-6 |
| Molecular Formula | C18H22FN3O |
| Molecular Weight | 315.39 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 315.39 g/mol gives (Z)-2-(2,2-dimethylpropanoyl)-3-[4-(2-fluorophenyl)piperazino]-2-propenenitrile distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
(Z)-2-(2,2-dimethylpropanoyl)-3-[4-(2-fluorophenyl)piperazino]-2-propenenitrile (CAS 1025124-66-6), molecular formula C18H22FN3O and molecular weight 315.39 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, (Z)-2-(2,2-dimethylpropanoyl)-3-[4-(2-fluorophenyl)piperazino]-2-propenenitrile is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 315.39 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (Z)-2-(2,2-dimethylpropanoyl)-3-[4-(2-fluorophenyl)piperazino]-2-propenenitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H22FN3O |
| Molecular Weight | 315.39 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Z Standards
- (Z)-2-(2,2-dimethylpropanoyl)-3-(4-phenylpiperazino)-2-propenenitrile (CAS 1020252-72-5)
- (Z)-2-(2,2-dimethylpropanoyl)-3-(4-piperidinophenyl)-2-propenenitrile (CAS 650595-00-9)
- 2-({3-[(2,2-Dimethylpropanoyl)amino]-anilino}carbonyl)cyclohexanecarboxylic acid 3820AF 940502-96-5 C19H26N2O4 (CAS 940502-96-5)
- 8-Benzyl-4-(2,2-dimethylpropanoyl)-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid (CAS 1326813-04-0)
- 4-{2-[1-(2,2-dimethylpropanoyl)-1H-indol-3-yl]ethyl}-1lambda6-thiomorpholine-1,1-dione (CAS 439111-69-0)
- 2-[(2,2-dimethylpropanoyl)amino]-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylic acid (CAS 790263-48-8)
- N-[3-(2,2-dimethylpropanoyl)pyridin-2-yl]-2,2-dimethylpropanamide (CAS 1864014-74-3)
- 3-[(2,2-Dimethylpropanoyl)amino][1,2,4]triazolo-[4,3-a]pyridine-8-carboxylic acid (CAS 1119452-13-9)
Recommended Standards
- 1-((1-Ethyl-3-methyl-1h-pyrazol-4-yl)sulfonyl)piperidine-3-carbohydrazide (CAS 1005627-84-8)
- N-(Benzo[d][1,3]dioxol-5-yl)-1-(thiophen-2-yl)cyclopentane-1-carboxamide (CAS 1049512-70-0)
- tert-butyl 3-fluoro-3-(3-methoxybenzoyl)azetidine-1-carboxylate (CAS 2507826-30-2)
- 2-(((1H-Benzo[d]imidazol-2-yl)sulfonyl)methyl)-N,N-dimethylaniline (CAS 105256-13-1)
- 4-Amino-3-iodo-5-nitrobenzoic acid (CAS 89677-77-0)
- 4-[4-(trifluoromethyl)phenyl]-1H-imidazol-2-amine (CAS 37148-87-1)
- 3-Hydroxy-5-(trifluoromethyl)phenylboronic Acid (CAS 957062-66-7)
- aluminum titanate (CAS 12004-39-6)
- 8-methylnaphthalen-1-amine (CAS 130523-30-7)
- 1-(3,4-Difluorophenyl)propan-1-ol (CAS 218449-99-1)
- 2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(naphthalen-1-yl)propanoic acid (CAS 176036-48-9)
- Benzyl 2-((5-(pyridin-4-yl)-1,3,4-oxadiazol-2-yl)thio)acetate (CAS 896376-66-2)
- 3-(Chlorodifluoromethyl)-8-nitro-[1,2,4]triazolo[4,3-a]pyridine (CAS 477889-58-0)
- Semaglutide impurity 199 (CAS CATO-C4X-2226199)
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