4-Chloro-6-(4-(3-(thiophen-2-yl)-1H-pyrazol-5-yl)piperidin-1-yl)pyrimidin-2-amine CAS 1025762-04-2

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-Chloro-6-(4-(3-(thiophen-2-yl)-1H-pyrazol-5-yl)piperidin-1-yl)pyrimidin-2-amine.

CATO supplies 4-Chloro-6-(4-(3-(thiophen-2-yl)-1H-pyrazol-5-yl)piperidin-1-yl)pyrimidin-2-amine (CAS 1025762-04-2), a certified reference material (molecular formula C16H17ClN6S, MW 360.86 g/mol) for analytical method development and quality control.

Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution, 4-Chloro-6-(4-(3-(thiophen-2-yl)-1H-pyrazol-5-yl)piperidin-1-yl)pyrimidin-2-amine is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 360.86 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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