8-Bromo-6-methylimidazo[1,2-a]pyrazine CAS 1025976-69-5

Purity 97%+In StockPharmaceutical Standards
CAS No.1025976-69-5
Molecular FormulaC7H6BrN3
Molecular Weight212.05 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

8-Bromo-6-methylimidazo[1,2-a]pyrazine CAS 1025976-69-5 chemical structure

Description

The occurrence of 8-Bromo-6-methylimidazo[1,2-a]pyrazine is closely related to a nitrile group, bromine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

8-Bromo-6-methylimidazo[1,2-a]pyrazine (CAS 1025976-69-5) is a high-purity analytical reference standard with the molecular formula C7H6BrN3 and a molecular weight of 212.05 g/mol.

The molecular framework of 8-Bromo-6-methylimidazo[1,2-a]pyrazine (C7H6BrN3) is characterized by a nitrile group, bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC7H6BrN3
Molecular Weight212.05 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1988
Halogen ContentBr-containing
Nitrogen Atoms3

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