1-(2-Nitrobenzenesulfonyl)-4-[5-(thiophen-2-yl)-1H-pyrazol-3-yl]piperidine CAS 1026099-77-3
| CAS No. | 1026099-77-3 |
| Molecular Formula | C18H18N4O4S2 |
| Molecular Weight | 418.49 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 1-(2-Nitrobenzenesulfonyl)-4-[5-(thiophen-2-yl)-1H-pyrazol-3-yl]piperidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
1-(2-Nitrobenzenesulfonyl)-4-[5-(thiophen-2-yl)-1H-pyrazol-3-yl]piperidine (CAS 1026099-77-3), molecular formula C18H18N4O4S2 and molecular weight 418.49 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-(2-Nitrobenzenesulfonyl)-4-[5-(thiophen-2-yl)-1H-pyrazol-3-yl]piperidine (C18H18N4O4S2) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C18H18N4O4S2 |
| Molecular Weight | 418.49 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 2 |
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Recommended Standards
- 3-[[[2-Methoxy-4-(phenylamino)phenyl]amino]sulfonyl]-2-thiophenecarboxylicacidmethylester (CAS 1014691-61-2)
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- 1,5-Bis(m-tolylamino)anthracene-9,10-dione (CAS 10114-49-5)
- (2-Phenyl-2H-1,2,3-triazol-4-yl)(4-(6-(piperidin-1-yl)pyrimidin-4-yl)piperazin-1-yl)methanone (CAS 1207004-27-0)
- 3-Bromo-4,5-dimethyl-1H-pyrrole-2-carboxylic acid (CAS 1216122-36-9)
- methyl 2-(1H-triazol-5-yl)acetate (CAS 1092286-86-6)
- 8-Fluoro-7-(trifluoromethyl)quinolin-4-ol (CAS 693818-12-1)
- 2-((4-Ethyl-5-(thiophen-2-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(m-tolyl)acetamide (CAS 557072-68-1)
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